114787-91-6

Basic information

• Product Name: 4-METHOXY-3-METHYLBENZYL ALCOHOL
• Synonyms: RARECHEM AL BD 0539;4-METHOXY-3-METHYLBENZYL ALCOHOL;(4-Methoxy-3-methyl-phenyl)-methanol
• CAS NO: 114787-91-6
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.19
• Product Categories: Benzhydrols, Benzyl & Special Alcohols
• Mol File: 114787-91-6.mol

Chemical Properties

• Boiling Point: 258.3 °C at 760 mmHg
• Flash Point: 110.8 °C
• Appearance: /
• Density: 1.06 g/cm³
• Vapor Pressure: 0.00707mmHg at 25°C
• Refractive Index: 1.528
• PKA: 14.43±0.10(Predicted)
• CAS DataBase Reference: 4-METHOXY-3-METHYLBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXY-3-METHYLBENZYL ALCOHOL(114787-91-6)
• EPA Substance Registry System: 4-METHOXY-3-METHYLBENZYL ALCOHOL(114787-91-6)

Safety Data

• Hazardous Substances Data: 114787-91-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-Methoxy-3-methylbenzyl alcohol is used as a starting material for the synthesis of various pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Chemical Production:
4-METHOXY-3-METHYLBENZYL ALCOHOL serves as a starting material for the production of other chemicals, playing a crucial role in the chemical industry.
Used in Perfumery and Flavor Industry:
4-Methoxy-3-methylbenzyl alcohol is used as a fragrance and flavoring agent in perfumes and food products, enhancing the sensory experience of these consumer goods.
Used in Anticancer Research:
4-Methoxy-3-methylbenzyl alcohol has been studied for its potential pharmacological properties, including its ability to inhibit the growth of certain cancer cells, indicating its possible use in cancer research and treatment.

InChI:InChI=1/C9H12O2/c1-7-5-8(6-10)3-4-9(7)11-2/h3-5,10H,6H2,1-2H3

Upstream product

• 60736-71-2 3-methyl-4-methoxybenzyl chloride 
• 127-09-3 sodium acetate 
• 32723-67-4 3-methyl-4-anisaldehyde 
• 14804-31-0 2-methyl-4-bromoanisole 
• 70347-04-5 4-Methoxy-3-methylbenzoesaeure-methylester 

Downstream Products

• 60736-71-2 3-methyl-4-methoxybenzyl chloride 
• 122488-89-5 3-methyl-4-methoxybenzyl bromide 
• 75391-57-0 2-(4-methoxy-3-methylphenyl)acetonitrile 
• 144341-72-0 (E)-2-(4-Methoxy-3-methyl-phenyl)-5,9-dimethyl-deca-4,8-dienenitrile 
• 144341-75-3 6-Methoxy-1,1,4a,7-tetramethyl-2-phenylsulfanyl-4,4a,10,10a-tetrahydro-1H-phenanthren-9-one 
• 144341-74-2 6-Methoxy-1,1,4a,7-tetramethyl-2-phenylsulfanyl-2,3,4,4a,10,10a-hexahydro-1H-phenanthren-9-one 
• 144341-87-7 2-Benzenesulfinyl-6-methoxy-1,1,4a,7-tetramethyl-2,3,4,4a,10,10a-hexahydro-1H-phenanthren-9-one 
• 144341-73-1 6-Methoxy-1,1,4a,7-tetramethyl-2-phenylsulfanyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-9-carbonitrile 
• 114787-92-7 3-(3-methyl-4-methoxyphenyl)methyl-N-BOC-histidine methyl ester 
• 1369423-32-4 diethyl 4-methoxy-3-methylbenzyl phosphate 

Relevant articles and documents

PYRIMIDINE COMPOUNDS CONTAINING ACIDIC GROUPS

The present disclosure relates to a class of pyrimidine derivatives having immunomodulating properties that act via TLR7 which are useful in the treatment of viral infections and cancers.

Acid-catalyzed reaction of 2-hydroxycyclobutanone with benzylic alcohols

The acid-promoted syntheses of 2-(benzyloxy)cyclobutanones and bis(benzyloxy)dioxatricyclo decanes were achieved starting from 2-hydroxycyclobutanone and variously functionalized benzyl alcohols. The reaction sequences afforded the desired products in good to high yields and in a solvent-dependent chemoselective fashion.

Benzylic phosphates as electrophiles in the palladium-catalyzed asymmetric benzylation of azlactones

Palladium-catalyzed asymmetric benzylation has been demonstrated with azlactones as prochiral nucleophiles in the presence of chiral bisphosphine ligands. Benzylic electrophiles are utilized under two sets of reaction conditions to construct a new tetrasubstituted stereocenter. Electron density of the phenyl ring dictates the reaction conditions, including the leaving group. The reported methodology represents a novel asymmetric carbon-carbon bond formation in an amino acid precursor.

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS

The present invention is directed to a compound of formula (I), or a pharmaceutically acceptable salt, solvate hydrate or stereoisomer thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.

Imidazopyridinone derivatives and their use as phosphodiesterase inhibitors

A compound (Ia): wherein the variables are defined in the specification, its prodrug or a pharmaceutically acceptable salt thereof useful in the treatment of angina, hypertension etc.

Diterpenes of Azadirachta indica. Syntheses to confirm structure

The structure of the diterpene nimbinone 1b has been confirmed by syntheses via a cascade cyclisation and also from podocarpic acid by two separate series of transformations. Synthesis of structure 3b from dehydroabietic acid shows that this does not exhibit the properties described for nimbosodione.

Synthesis and antirhinovirus activity of 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)-9H-purines

A series of 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)purines was synthesized and tested for antirhinovirus activity. Most of the compounds were synthesized by alkylation of 6-chloro-2-(trifluoromethyl)-9H-purine with the appropriate benzyl halide followed by displacement of the chloro group with dimethylamine. Alternatively, 6-(dimethylamino)-2-(trifluoromethyl)purine was alkylated with the appropriate benzyl halide. Although several different aryl substituents provided compounds with IC50's = 0.03 μM against rhinovirus serotype 1B, no congener was significantly more active than the parent 2. Twenty-three compounds were tested against 18 other serotypes, but none exhibited a uniform profile of activity.