115184-32-2

Basic information

• Product Name: 2-(L-RHAMNO-TETRAHYDROXYPENTYL)-4(R)-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID
• Synonyms: 2-(L-RHAMNO-TETRAHYDROXYPENTYL)-4(R)-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID;[2R-[2alpha(R*),4alpha]]-1-C-(4-Carboxy-2-thiazolidinyl)-5-deoxy-L-arabinitol
• CAS NO: 115184-32-2
• Molecular Formula: C9H17NO6S
• Molecular Weight: 267.3
• Mol File: 115184-32-2.mol

Chemical Properties

• Boiling Point: 633.0±55.0 °C(Predicted)
• Appearance: /
• Density: 1.547±0.06 g/cm3(Predicted)
• PKA: 1.97±0.40(Predicted)
• CAS DataBase Reference: 2-(L-RHAMNO-TETRAHYDROXYPENTYL)-4(R)-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(L-RHAMNO-TETRAHYDROXYPENTYL)-4(R)-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID(115184-32-2)
• EPA Substance Registry System: 2-(L-RHAMNO-TETRAHYDROXYPENTYL)-4(R)-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID(115184-32-2)

Safety Data

• Hazardous Substances Data: 115184-32-2(Hazardous Substances Data)

Usage

Molecular structure

2-(L-rhamno-tetrahydroxypentyl)-4(R)-1,3-thiazolidine-4-carboxylic acid is a thiazolidine carboxylic acid derivative that contains a unique rhamnose moiety.

Pharmacological and therapeutic applications

The compound has potential pharmacological and therapeutic applications due to its ability to interact with cellular and molecular targets.

Thiazolidine ring

The presence of a thiazolidine ring in the molecule makes it an interesting candidate for drug development, as thiazolidines are known to exhibit various biological activities.

Carboxylic acid group

The presence of a carboxylic acid group in this compound provides opportunities for further modifications and derivatization to enhance its biological properties.

Novel and versatile scaffold

This chemical represents a novel and versatile scaffold for the development of new pharmaceutical agents.

Upstream product

• 52-90-4 L-Cysteine 
• 3615-41-6 L-Rhamnose 
• 52-89-1 l-cysteine hydrochloride 
• 124704-85-4 kaempferol 3-O-β-D-xylopyranosyl-(1→2)-α-L-rhamnopyranosyl-7-O-α-L-rhamnopyranoside 
• 18598-63-5 L-cysteine methyl ester hydrochloride 
• 1415248-05-3 kaempferol 3-O-β-D-xylopyranosyl-(1→2)-α-L-arabinofuranosyl-7-O-α-L-rhamnopyranoside 
• 2438-80-4 L-Fucose 

Relevant articles and documents

Kaempferol glycosides from the twigs of Cinnamomum osmophloeum and their nitric oxide production inhibitory activities

In the present study, ethanolic extract of twigs from Cinnamomum osmophloeum led to isolate nine kaempferol glycosides including two new kaempferol triglycosides that were characterized as kaempferol 3-O-β-d-xylopyranosyl-(1→2)-α-l-arabinofuranosyl-7-O-α-

Proton and Zinc(II) Complexes of 2-(Polyhydroxyalkyl)thiazolidine-4-carboxylic acid Derivatives

The protonation and zinc-ion co-ordination equilibria of 2-(polyhydroxyalkyl)thiazolidine-4-carboxylic acid derivatives have been studied by potentiometric titration in the range pH 1.5-8.In most cases the formation of complexes with a metal-to-ligand ratio of 1:2 was demonstrated, but at above pH 6 mixed-ligand complexes involving hydroxide-ion co-ordination were also observed.The protonation and complex-formation constants were shown to depend on the structure of the polyhydroxy chains.In the case of the protonation constants this is due to the rearrangement of the intramolecular hydrogen-bonding network, while the complex-formation constants depend on the conformation of the OH groups on the first carbon atoms of the polyol chains.

Thiazolidine-4(R)-carboxylic acids derived from sugars: Part I, C2-epimerisation in aqueous solutions.

Reactions of L-cysteine (1) with L-xylose, D-ribose, D-lyxose, D-arabnose, D-glucose, L-rhamnose, and-fucose in aqueoes ethanol yielded crystalline 2(S)-(polihydroxyalkyl)thiazolidine-4(R)-carboxylic acids.Likewise, glycolaldehyde and L-glyceraldehyde, D-xylose, L-arabinose, D-mannose, D-galactose, and D-fucose gave crystalline 2(R),4(R) epimers.The reaction of 1 and D-glycerinaldehyde gave a syrup mixture of 2(S),4(R) and 2(R),4(R) compounds.The same substrates, but with no ethanol present, gave the 2(S),4(R) epimers for glycolaldehyde, L-xylose, L-fucose, and L-arabinose, and the 2(R),4(R) epimers for D-lyxose, L-rhamnose, D-mannose, Dgalactose, and D-fucose.The reactions of D-ribose, D-arabinose, D-xylose, and D-glucose gave sirupy mixtures of epimers.The crystalline reaction products, when dissolved in water, undergo rapid epimerisation as reflected by mutarotation and changes in the 1H- and 13C-n.m.r. spectra.