- An efficient one-pot synthesis of 5-(substituted amino)-1,2,4-thia- and -oxa-diazoles
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A general protocol for the synthesis of 5-(substituted amino)-1,2,4- thiadiazoles by the cyclocondensation reaction of amidoximes with N-substituted thioureas in the presence of KF/Al2O3, and of 5-(cyclohexylamino)-1,2,4-oxadiazoles with DCC in the presence of KF/Al 2O3 and thiourea, is described. The structures of the new compounds were elucidated by spectroscopic and physical data, and the crystal structure determination by X-ray diffraction of three examples.
- Dueruest, Yasar,Yildirim, Muhammet,Aycan, Asli
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experimental part
p. 235 - 239
(2009/08/07)
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