- A METHOD FOR THE PREPARATION OF 6,7-DIMETHOXY-1-[2-(4-TRIFLUOROMETHYLPHENYL)ETHYL]-3,4- DIHYDROISOQUINOLINE
-
The invention relates to a method of preparing 6,7-dimethoxy-l-[2-(4-trifluoromethylphenyl) ethyl]-3,4-dihydroisoquinoline I by cyclization of substance III, wherein the R substituent is a C1-C4 alkyl group, under conditions of acidic catalysis, the acidi
- -
-
Page/Page column 6
(2011/08/03)
-
- METHOD FOR OBTAINING AN OPTICALLY PURE 1,2,3,4 TETRAHYDRO-ISOQUINOLINE DERIVATIVE
-
The invention relates to a method for obtaining enantiomerically enriched 6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-1,2,3,4-tetrahydro-isoquinoline from a mixture of (R)-6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-1,2,3,4-tetrahydro-isoquinoline and (S)-6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-1,2,3,4-tetrahydro-isoquinoline.
- -
-
Page/Page column 26
(2010/06/20)
-
- PROCESS FOR THE PREPARATION OF AN ENANTIOMERIC TRISUBSTITUTED 3,4-DIHYDRO-ISOQUINOLINE DERIVATIVE
-
The present invention relates to a process for the preparation of the compound of formula (7) which process comprises the hydrogenation of the compound of formula (4) using bis[chloro-1,5-cyclooctadiene-iridium], (S)-i -dicyclohexylphosphino- 2-[(S)-α-(di
- -
-
Page/Page column 7; 19
(2009/08/14)
-
- TRISUBSTITUTED 3,4-DIHYDRO-1H-ISOQUINOLIN COMPOUND, PROCESS FOR ITS PREPARATION, AND ITS USE
-
The present invention relates to the compound of formula (7*)acetate (see below), a process for its preparation, and its use.
- -
-
Page/Page column 7; 19
(2009/08/14)
-