118160-07-9

Basic information

• Product Name: 1(2H)-Isoquinolinone,2,7-dimethyl-(9CI)
• Synonyms: 1(2H)-Isoquinolinone,2,7-dimethyl-(9CI)
• CAS NO: 118160-07-9
• Molecular Formula: C11H11NO
• Molecular Weight: 173.21114
• Product Categories: QUINOLINONE
• Mol File: 118160-07-9.mol

Chemical Properties

• Boiling Point: 150 °C(Press: 2 Torr)
• Appearance: /
• Density: 1.129±0.06 g/cm3(Predicted)
• PKA: -2.09±0.70(Predicted)
• CAS DataBase Reference: 1(2H)-Isoquinolinone,2,7-dimethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Isoquinolinone,2,7-dimethyl-(9CI)(118160-07-9)
• EPA Substance Registry System: 1(2H)-Isoquinolinone,2,7-dimethyl-(9CI)(118160-07-9)

Safety Data

• Hazardous Substances Data: 118160-07-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1(2H)-Isoquinolinone, 2,7-dimethyl-(9CI) is used as a building block for the synthesis of other compounds, particularly in the pharmaceutical industry. Its unique chemical structure allows it to be a key component in the development of new drugs and therapeutic agents.
Used in Material Development:
1(2H)-Isoquinolinone,2,7-dimethyl-(9CI) also has potential applications in the development of new materials due to its chemical properties and reactivity with other substances. It can be used to create novel materials with specific characteristics for various industries.
Used as a Research Tool:
1(2H)-Isoquinolinone, 2,7-dimethyl-(9CI) serves as a valuable research tool in chemical and biological studies. Its unique properties and reactivity make it an important compound for understanding various chemical reactions and biological processes.
It is important to handle 1(2H)-Isoquinolinone, 2,7-dimethyl-(9CI) with care, as it can be hazardous if not properly managed. Proper safety measures should be taken to ensure the safe use of this compound in various applications.

Upstream product

• 118160-10-4 (4aS,8aR)-4a-Acetyl-2,7-dimethyl-4a,5,8,8a-tetrahydro-2H-isoquinolin-1-one 
• 74041-72-8 trans-4a-cyano-4a,5,8,8a-tetrahydro-2,7-dimethyl-1(2H)-isoquinolone 
• 74041-72-8 cis-4a-cyano-4a,5,8,8a-tetrahydro-2,7-dimethyl-1(2H)-isoquinolone 
• 74041-71-7 trans-2,7-dimethyl-4a-methoxycarbonyl-4a,5,8,8a-tetrahydro-1(2H)-isoquinolone 
• 74041-71-7 cis-4a,5,8,8a-tetrahydro-4a-methoxycarbonyl-2,7-dimethyl-1(2H)-isoquinolone 
• 27330-27-4 4-acetyl-1-methylpyridin-2(1H)-one 
• 70411-83-5 1-methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile 
• 20845-23-2 methyl 1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylate 
• 118160-09-1 (4aS,8aR)-4a-Acetyl-2,6,7-trimethyl-4a,5,8,8a-tetrahydro-2H-isoquinolin-1-one 
• 78-79-5 isoprene 
• 872-36-6 vinylene carbonate 
• 74786-81-5 m-methyl-N-methylbenzamide 

Relevant articles and documents

Co(III)-Catalyzed Annulative Vinylene Transfer via C-H Activation: Three-Step Total Synthesis of 8-Oxopseudopalmatine and Oxopalmatine

The Co(III)-catalyzed redox-neutral annulation of benzamides and acrylamides with vinylene carbonate for the synthesis of isoquinolinones and pyridinones has been developed. This protocol employing inexpensive Co(III) as the catalyst tolerated diverse functional groups and substitution patterns, affording the target products with good to excellent yields. The synthetic utility of this transformation was demonstrated by a three-step synthesis of gusanlung D, 8-oxopseudopalmatine, and oxopalmatine.

Studies on 1-Alkyl-2(1H)-pyridone Derivatives. XXXI. Syntheses of Isoquinoline Derivatives Using Diels-Alder Reaction of 4-Acetyl-, 4-Cyano-, and 4-Methoxycarbonyl-1-methyl-2(1H)-pyridones with 1,3-Butadiene Derivatives

The Diels-Alder reaction of 4-cyano-, 4-methoxycarbonyl-, and 4-acetyl-2(1H)-pyridones (I, II, and IV) with 1,3-butadiene derivatives (III and V) were carried out to give 4a-substituted tetrahydro-1(2H)-isoquinolone derivatives (VI-IX, XV, XIX, and XX).