118343-81-0Relevant articles and documents
Enantioselective intramolecular aldehyde α-alkylation with simple olefins: Direct access to homo-ene products
Comito, Robert J.,Finelli, Fernanda G.,Macmillan, David W. C.
supporting information, p. 9358 - 9361 (2013/07/26)
A highly selective method for the synthesis of asymmetrically substituted carbocycles and heterocycles from unactivated aldehyde-olefin precursors has been achieved via enantioselective SOMO-catalysis. Addition of a catalytically generated enamine radical cation across a pendent olefin serves to establish a general asymmetric strategy toward the production of a wide range of formyl-substituted rings with alkene transposition. Conceptually, this novel mechanism allows direct access to "homo-ene"-type products.
Efficient platinum(II) catalyzed hydroformylation reaction in water: Unusual product distribution in micellar media
Gottardo, Marina,Scarso, Alessandro,Paganelli, Stefano,Strukul, Giorgio
experimental part, p. 2251 - 2262 (2010/12/25)
The hydroformylation of a variety of terminal and internal alkenes is efficiently performed by cationic platinum triflate complexes of the type [P2Pt(H2O)2](OTf)2 under mild conditions in an aqueous micellar medium. The use of surfactants is essential to ensure dissolution of the catalyst and substrate in water with catalysts being positioned on the anionic surface of the micelles. Aldehydes are obtained with linear to branched ratios up to >99:1. With styrene derivatives also the corresponding benzaldehydes are formed. The catalyst can be separated by extraction of the organic products with hexane and recycled for at least four times with only a modest loss of activity and no effect on selectivity.
