147974-19-4

Usage

Uses

Used in Chemical Synthesis:
Heptanal, 7-[[(1,1-dimethylethyl)diphenylsilyl]oxy]is used as a building block in chemical synthesis for creating more complex organic molecules. Its unique functional group can participate in various chemical reactions, enabling the synthesis of novel compounds with specific properties.
Used in Materials Science:
In the field of materials science, Heptanal, 7-[[(1,1-dimethylethyl)diphenylsilyl]oxy]can be used as a component in the development of new materials with tailored properties. Its chemical structure may contribute to the formation of specific material characteristics, such as improved solubility, reactivity, or stability.
Used in Pharmaceutical Industry:
Heptanal, 7-[[(1,1-dimethylethyl)diphenylsilyl]oxy]may be utilized in the pharmaceutical industry as a precursor for the synthesis of bioactive compounds or as a modifier to enhance the properties of existing drugs. Its unique structure could potentially improve drug delivery, bioavailability, or therapeutic efficacy.
Used in Analytical Chemistry:
In analytical chemistry, Heptanal, 7-[[(1,1-dimethylethyl)diphenylsilyl]oxy]can be employed as a reference compound or a standard for the development and validation of analytical methods. Its distinct chemical properties may be useful for calibrating instruments or comparing the performance of different analytical techniques.
Used in Research and Development:
Heptanal, 7-[[(1,1-dimethylethyl)diphenylsilyl]oxy]serves as a valuable compound for research and development purposes. Its unique structure and potential applications in various fields make it an interesting subject for further investigation, leading to the discovery of new uses and insights into its properties.

Upstream product

• 22054-13-3 7-hydroxyheptanal 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 629-30-1 1,7-heptandiol 
• 191476-08-1 7-((tert-butyldiphenylsilyl)oxy)heptan-1-ol 

Downstream Products

• 147974-22-9 (R)-8-hydroxyoctan-2-ol-8-tert-butyldiphenylsilyl ether 
• 885041-63-4 8-tert-butyldiphenylsilyloxy-1,1-dibromooct-1-ene 
• 285998-56-3 9-(tert-butyl-diphenyl-silanyloxy)-non-2-enoic acid methyl ester 
• 1171123-87-7 C₃₅H₄₃N₃OSi 
• 118343-81-0 8-methylnon-7-enal 
• 1443054-67-8 (1R,2R)-2-(prop-1-en-2-yl)cyclohexanecarbaldehyde 
• 1443054-32-7 tert-butyl(8-methylnon-7-enyloxy)diphenylsilane 

Relevant academic research and scientific papers

Structure-activity relationship of biakamide, selective growth inhibitors under nutrient-starved condition from marine sponge

The tumor microenvironment is considered as one of the important targets for anticancer drug discovery. In particular, nutrient deficiency may be observed in tumor microenvironment; biakamides A-D (1-4) isolated from marine sponge Petrosaspongia sp. as gr

IDEBENONE COMPOUNDS

The present application provides idebenone derivatives or analogues useful for treating a disease or disorder in a subject in need thereof. Pharmaceutical compositions comprising the compounds and methods of treating the disease or disorder are also provided.

Design, Synthesis and Biological Evaluation of Highly Potent Simplified Archazolids

The archazolids are potent antiproliferative compounds that have recently emerged as a novel class of promising anticancer agents. Their complex macrolide structures and scarce natural supply make the development of more readily available analogues highly important. Herein, we report the design, synthesis and biological evaluation of four simplified and partially saturated archazolid derivatives. We also reveal important structure-activity relationship data as well as insights into the pharmacophore of these complex polyketides.

Development of Hybrid Phospholipid Mimics as Effective Agonists for Liver Receptor Homologue-1

The orphan nuclear receptor Liver Receptor Homologue-1 (LRH-1) is an emerging drug target for metabolic disorders. The most effective known LRH-1 modulators are phospholipids or synthetic hexahydropentalene compounds. While both classes have micromolar ef

Enantioselective intramolecular aldehyde α-alkylation with simple olefins: Direct access to homo-ene products

A highly selective method for the synthesis of asymmetrically substituted carbocycles and heterocycles from unactivated aldehyde-olefin precursors has been achieved via enantioselective SOMO-catalysis. Addition of a catalytically generated enamine radical cation across a pendent olefin serves to establish a general asymmetric strategy toward the production of a wide range of formyl-substituted rings with alkene transposition. Conceptually, this novel mechanism allows direct access to "homo-ene"-type products.

Enantioselective synthesis of cyclopropyl δ-lactonealdehydes and dodecyl-5-ene-1-yne-3-ol: Advanced intermediates of solandelactone A and B

A stereocontrolled synthesis of cyclopropyl δ-lactonealdehydes and dodecyl-5-ene-1-yne-3-ol is accomplished with predictable absolute stereochemistry via organocatalytic and catalytic asymmetric transfer hydrogenation reactions. The salient feature of this protocol is the genesis of chirality through an organocatalytic reaction and utilized for installing a critical bifunctional trans-cyclopropane motif, which is a key segment of every representative member of the oxylipin class of natural products such as solandelactone A and B.

Development of a concise and diversity-oriented approach for the synthesis of plecomacrolides via the diene-ene RCM

A concise synthesis of the core structures of plecomacrolide with ring sizes varying from 16 to 19 atoms was achieved for the first time by the diene-ene ring-closing olefin metathesis reaction. This approach should allow access to the structurally divers

20-Hydroxyeicosatetraenoic Acid (20-HETE): Structural Determinants for Renal Vasoconstriction

The effects of natural and synthetic eicosanoids on the diameter of rat interlobular arteries studied in vitro were compared to that of the potent, endogenous vasoconstrictor 20-HETE. Vasoconstrictor activity was optimum for chain lengths of 20 - 22 carbo

Polymer-supported sulfinimidoyl chlorides: A convenient reagent for oxidation of alcohols

Two polymer-supported sulfinimidoyl chlorides, i.e., 4-(N-tert-butylchlorosulfinimidoyl)phenoxymethylpolystyrene (3) and 4-(N-tert-butylchlorosulfinimidoyl)polystyrene (10), were prepared from chloromethylpolystyrene and polystyrene, respectively. Stoichiometric or catalytic oxidation of various primary and secondary alcohols using these polymer-supported sulfinimidoyl chlorides proceeded smoothly, and the corresponding aldehydes and ketones were conveniently prepared in good-to-high yields by simple work-up procedures. The polymer-supported oxidant 10 was recycled repeatedly by chlorination of a used polymer 11 with N-chlorosuccinimide (NCS) after stoichiometric oxidation.

Sulfenamide-catalyzed oxidation of primary and secondary alcohols with molecular bromine

Primary and secondary alcohols were smoothly oxidized to the corresponding aldehydes and ketones in high yields at room temperature with 1.1 equiv. of molecular bromine by using a catalytic amount of N-t-butyl-2-nitrobenzenesulfenamide in the coexistence of potassium carbonate and molecular sieves 4A.