119448-87-2Relevant articles and documents
Divergent and Regioselective Synthesis of Pyrazolo[1,5- a]pyridines and Imidazo[1,5- a]pyridines
Mennie, Katrina M.,Reutershan, Michael H.,White, Catherine,Adams, Bruce,Becker, Bridget,Deng, James,Katz, Jason D.,Lablue, Elisabeth,Margrey, Kaila,Saurí, Josep
supporting information, p. 4694 - 4698 (2021/06/28)
Nitrogenous heterocycles are ubiquitous in pharmaceuticals and drug-like compounds; however, regioselective synthesis has proved challenging. Herein we report our efforts to develop a regioselective method for the synthesis of pyrazolo[1,5-a]pyridines and the serendipitous discovery of a protocol for the regioselective formation of imidazo[1,5-a]pyridines. Together, these transformations allow for the rapid and selective formation of two important heterocyclic motifs from a common intermediate.
A New Route to Imidazo(1,5-a)pyridines and -quinolines
Kolar, Patrik,Tisler, Miha
, p. 1110 - 1112 (2007/10/02)
Heterocyclic Amino Acids, Imidazo(1,5-a)pyridine and imidazo(1,5-a)quinoline, Benzoquinolizin-1-one A new synthetic approach for imidazo(1,5-a)pyridines and imidazo(1,5-a)quinolizines from the corresponding alkyl(pyridyl-2')- or (quinolyl-2')glycinates is described.