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PHENOTHIAZINE-5-OXIDE, also known as 10H-Phenothiazine 5-Oxide, is a chemical compound that serves as a by-product in the synthesis of Phenothiazine S,S-Dioxide (P297600). Phenothiazine S,S-Dioxide is a derivative of Phenothiazine (P318040), which is a key component of antipsychotic and antihistaminic drugs. PHENOTHIAZINE-5-OXIDE is characterized by its unique chemical structure and properties, making it a potential candidate for various applications in different industries.

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  • 1207-71-2 Structure
  • Basic information

    1. Product Name: PHENOTHIAZINE-5-OXIDE
    2. Synonyms: 10H-Phenothiazine, 5-oxide;Phenothiazine S-oxide;USAF do-16;AKOS 93707;PHENOTHIAZINE-5-OXIDE
    3. CAS NO:1207-71-2
    4. Molecular Formula: C12H9NOS
    5. Molecular Weight: 215.27
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1207-71-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 433.3°C at 760 mmHg
    3. Flash Point: 215.9°C
    4. Appearance: /
    5. Density: 1.44g/cm3
    6. Vapor Pressure: 1.03E-07mmHg at 25°C
    7. Refractive Index: 1.769
    8. Storage Temp.: Room Temperature, under inert atmosphere
    9. Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
    10. CAS DataBase Reference: PHENOTHIAZINE-5-OXIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: PHENOTHIAZINE-5-OXIDE(1207-71-2)
    12. EPA Substance Registry System: PHENOTHIAZINE-5-OXIDE(1207-71-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1207-71-2(Hazardous Substances Data)

1207-71-2 Usage

Uses

Used in Pharmaceutical Industry:
PHENOTHIAZINE-5-OXIDE is used as an intermediate in the synthesis of Phenothiazine S,S-Dioxide, which is a key component in the development of antipsychotic and antihistaminic drugs. Its presence in the synthesis process contributes to the production of these essential medications, helping to treat various mental health conditions and allergies.
Used in Chemical Research:
PHENOTHIAZINE-5-OXIDE can be utilized as a research compound in the field of chemistry, particularly in the study of Phenothiazine derivatives and their potential applications. Its unique chemical properties and structure make it a valuable subject for scientific investigation, potentially leading to the discovery of new uses and applications for this compound.
Used in Material Science:
PHENOTHIAZINE-5-OXIDE may also find applications in material science, where its unique properties can be harnessed to develop new materials with specific characteristics. Its potential use in this field could lead to advancements in various industries, such as electronics, textiles, and coatings, among others.

Check Digit Verification of cas no

The CAS Registry Mumber 1207-71-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,0 and 7 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1207-71:
(6*1)+(5*2)+(4*0)+(3*7)+(2*7)+(1*1)=52
52 % 10 = 2
So 1207-71-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H9NOS/c14-15-11-7-3-1-5-9(11)13-10-6-2-4-8-12(10)15/h1-8,13H

1207-71-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 10H-phenothiazine 5-oxide

1.2 Other means of identification

Product number -
Other names phenothiazine sulfoxyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1207-71-2 SDS

1207-71-2Related news

Luminescence properties of PPV-based conjugated polymers containing phenothiazine and PHENOTHIAZINE-5-OXIDE (cas 1207-71-2) units07/18/2019

The photo-physical and electroluminescent properties of five PPV-type conjugated polymers containing phenothiazine and phenothiazine-5-oxide moieties were studied by UV–vis, PL and EL methods. The polymers showed PL maxima in the range 546-553 nm in solution and is 574–589 nm in solid. Red shi...detailed

1207-71-2Relevant articles and documents

Ozonization of phenothiazine and its analogues

Matsui,Miyamoto,Shibata,Takase

, p. 2526 - 2530 (1984)

When phenothiazine and phenoxazine were ozonized in dichloromethane, the cation radicals and the ozonate anion radicals were detected, whereas, in the ozonization of phenoxathiin and thianthrene, these radicals were not observed. Formation of these radicals was more favorable as greater was the polarity of the solvent and lower was the oxidation potential of the substrate. Ozonization of phenothiazine and phenoxazine in polar solvents was explained by the electron-transfer mechanism accompanied by the electrophilic ozone attack, and that of phenoxathiin and thianthrene by the electrophilic ozone attack alone.

Metal substitution in thermolysin: Catalytic properties of tungstate thermolysin in sulfoxidation with H2O2

Bakker, Martin,Van Rantwijk, Fred,Sheldon, Roger A.

, p. 622 - 625 (2007/10/03)

The catalytic Zn2+ ion was extracted from thermolysin, which had been covalently bound to Eupergit C. The apo-enzyme incorporated the oxometallate anions MoO42-, SeO42-, and WO42- with partial restoration of the proteolytic activity. Tungstate thermolysin was moderately active in the sulfoxidation of thioanisole by hydrogen peroxide, whereas its activity towards phenylmercaptoacetophenone, which was designed to bind well in the active site of thermolysin, was much higher.

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