121933-60-6

Basic information

• Product Name: 4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBALDEHYDE
• Synonyms: 4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBALDEHYDE;4-Methyl-4H-thieno[3,2-b]pyrrol-5-carbaldehyde;4H-thieno[3,2-b]pyrrole-5-carbaldehyde
• CAS NO: 121933-60-6
• Molecular Formula: C₈H₇NOS
• Molecular Weight: 165.21
• Mol File: 121933-60-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBALDEHYDE(121933-60-6)
• EPA Substance Registry System: 4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBALDEHYDE(121933-60-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 121933-60-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBALDEHYDE is used as a key intermediate in organic synthesis for the construction of complex organic molecules. Its unique structure and reactivity facilitate the formation of various chemical bonds, making it a versatile component in the synthesis of a wide range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBALDEHYDE is utilized as a building block for the development of new drugs. Its structural features and reactivity enable the design and synthesis of novel drug candidates with potential therapeutic applications.
Used in Material Science:
4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBALDEHYDE may also find applications in the development of new materials due to its interesting structural features. Its properties and reactivity could contribute to the creation of innovative materials with unique properties and potential applications in various fields.
Used in Chemical Research and Development:
As a significant component in the field of chemical research and development, 4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBALDEHYDE is employed in various research projects to explore its properties, reactivity, and potential applications. Its unique structure and reactivity make it an important subject of study for advancing the understanding of chemical reactions and the development of new synthetic methods.

Upstream product

• 121933-59-3 (4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol 
• 106200-65-1 ethyl-4‐methyl‐4H‐thieno[3,2‐b]pyrro‐5‐carboxylate 
• 82782-85-2 thieno<3,2-b>pyrrole-5-carboxylic acid methyl ester 
• 857284-01-6 methyl 4-methyl-4H-thieno[3,2-b]pyrrole-5-carboxylate 

Downstream Products

• 1410884-68-2 N-(2-(tert-butylamino)-1-(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)-2-oxoethyl)-N-(4-methoxybenzyl)but-2-ynamide 

Relevant articles and documents

Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models

Lysine-specific demethylase 1 (LSD1 or KDM1A) is a FAD-dependent enzyme that acts as a transcription corepressor or coactivator by regulating the methylation status of histone H3 lysines K4 and K9, respectively. KDM1A represents an attractive target for c

Synthesis of N-Substituted Methyl 4H-Thieno[3,2-b]pyrrole-5-carboxylates

The alkylation of methyl 4H-thieno[3,2-b]pyrrole-5-carboxylate with methyl iodide and allyl, propargyl, and benzyl bromides in the presence of sodium hydride in THF afforded the corresponding N-substituted derivatives. Some reactions of the alkylation products were studied.

A SYNTHESIS OF 4,7-DIHYDRO-1H-DIPYRROLOPYRROLE AND 4,7-DIHYDRO-4H-THIENOPYRROLOPYRROLE SYSTEMS

The titled two systems (3 and 6), both new members of linearly fused heteroaromatics, were prepared using pyrrolo-annulation reaction: condensation of an aromatic aldehyde with azidoacetate followed by thermolysis of the resulting azidoacrylate.