4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde

Base Information

Chemical Name:4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde
CAS No.:121933-60-6
Molecular Formula:C8H7 N O S
Molecular Weight:165.216
Hs Code.:
DSSTox Substance ID:DTXSID50428199
Wikidata:Q82240996
Mol file:121933-60-6.mol

Synonyms:4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde;121933-60-6;4-methylthieno[3,2-b]pyrrole-5-carbaldehyde;4H-Thieno[3,2-b]pyrrole-5-carboxaldehyde, 4-methyl-;SCHEMBL1788259;DTXSID50428199;XFKPNQZVRPOJNA-UHFFFAOYSA-N;MFCD07772837;AKOS006282098;AT18495;WS-02814;CS-0324762;W-205132;4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde, AldrichCPR

Suppliers and Price of 4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde
10mg
$ 45.00

American Custom Chemicals Corporation
4-METHYL-4H-THIENO[3,2-B]PYRROLE-5-CARBALDEHYDE 95.00%
1G
$ 907.14

Aaron Chemicals
4H-Thieno[3,2-b]pyrrole-5-carboxaldehyde,4-methyl- 95%
1g
$ 372.00

Aaron Chemicals
4H-Thieno[3,2-b]pyrrole-5-carboxaldehyde,4-methyl- 95%
100mg
$ 116.00

Total 9 raw suppliers

Chemical Property of 4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde

Chemical Property:

PSA：50.24000
LogP:2.05230
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:165.02483502
Heavy Atom Count:11
Complexity:174

Purity/Quality:

98%min ^*data from raw suppliers

4-Methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C=C1C=O)SC=C2

Technology Process of 4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde

There total 4 articles about 4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 121933-59-3
(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol

: 121933-60-6
4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde

Guidance literature:: With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 20h; Inert atmosphere;
DOI:10.1021/acsmedchemlett.9b00604

Reference yield:

: 82782-85-2
thieno<3,2-b>pyrrole-5-carboxylic acid methyl ester

: 121933-60-6
4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.25 h / Inert atmosphere

1.2: Inert atmosphere; Heating

2.1: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere

3.1: [bis(acetoxy)iodo]benzene; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane / 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; sodium hydride; In tetrahydrofuran; dichloromethane; mineral oil;
DOI:10.1134/S1070428018060131

Reference yield:

: 106200-65-1
ethyl-4‐methyl‐4H‐thieno[3,2‐b]pyrro‐5‐carboxylate

: 121933-60-6
4-methyl-4H-thieno[3,2-b]pyrrole-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: DIBAL-H

2: nickel peroxide

With nickel(IV) oxide; diisobutylaluminium hydride;
DOI:10.1016/S0040-4039(00)99545-5