122-27-0

Basic information

• Product Name: M-CRESYL PHENYLACETATE
• Synonyms: Benzeneaceticacid,3-methylphenylester;m-Cresyl alpha-toluate;meta-Tolyl phenylacetate;m-tolyl;META-CRESYLPHENYLACETATE;Phenylacetic acid 3-methylphenyl ester;(3-methylphenyl) 2-phenylacetate;(3-methylphenyl) 2-phenylethanoate
• CAS NO: 122-27-0
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.27
• EINECS: 204-531-0
• Mol File: 122-27-0.mol

Chemical Properties

• Boiling Point: 359.1°Cat760mmHg
• Flash Point: 122.2°C
• Appearance: /
• Density: 1.108g/cm³
• Vapor Pressure: 2.44E-05mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: M-CRESYL PHENYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: M-CRESYL PHENYLACETATE(122-27-0)
• EPA Substance Registry System: M-CRESYL PHENYLACETATE(122-27-0)

Safety Data

• Hazardous Substances Data: 122-27-0(Hazardous Substances Data)

Usage

Uses

Used in Fragrance and Flavor Industry:
M-Cresyl phenylacetate is used as a scenting agent for its distinctive sweet, fruity, and floral aroma, enhancing the sensory experience of various products.
Used in Cosmetics and Personal Care Products:
In the cosmetics and personal care industry, M-Cresyl phenylacetate serves as a fragrance ingredient, adding a pleasant scent to soaps, lotions, and other products to improve consumer appeal.
Used in Pharmaceutical Industry:
M-Cresyl phenylacetate is utilized as a potential drug candidate in the pharmaceutical sector, indicating its potential therapeutic applications.
Used in Antimicrobial Research:
M-CRESYL PHENYLACETATE has been studied for its antimicrobial properties, suggesting its use in developing new antimicrobial agents to combat resistant pathogens.
Overall, M-Cresyl phenylacetate is a versatile chemical with applications spanning across fragrances, cosmetics, pharmaceuticals, and antimicrobial research, highlighting its importance in multiple industries.

InChI:InChI=1/C15H14O2/c1-12-6-5-9-14(10-12)17-15(16)11-13-7-3-2-4-8-13/h2-10H,11H2,1H3

Upstream product

• 103-82-2 phenylacetic acid 
• 108-39-4 3-methyl-phenol 
• 3669-50-9 1-(4-hydroxy-2-methylphenyl)-2-phenylethan-1-one 
• 2491-34-1 1-(2-hydroxy-4-methylphenyl)-2-phenylethan-1-one 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 2491-34-1 1-(2-hydroxy-4-methylphenyl)-2-phenylethan-1-one 
• 137937-39-4 1-(2-hydroxy-6-methylphenyl)-2-phenylethanone 
• 3669-50-9 1-(4-hydroxy-2-methylphenyl)-2-phenylethan-1-one 

Relevant articles and documents

Synthesis of 7-hydroxy-6H-naphtho[2,3-c]coumarinviaa TsOH-mediated tandem reaction

A concise and efficient method for the synthesis of 7-hydroxy-6H-naphtho[2,3-c]coumarin using available 1-(2-hydroxyphenyl)-2-phenylethanone and Meldrum's acid has been developed. This transformation involved a tandem aldol reaction/lactonization/Friedel-Crafts reaction to form a lactone ring and a benzene ring. It showed high atom economy with water and acetone as the byproducts. Mechanism studies demonstrated two roles of Meldrum's acid: (i) as the reagent for the tandem reaction, and (ii) as the catalyst for the Friedel-Crafts reaction. Moreover, the hydroxyl group of 7-hydroxy-6H-naphtho[2,3-c]coumarin was further functionalized efficiently by arylethynyl, aryl, and cyano groups to furnish D-π-A compounds with excellent fluorescence emissions (ΦF= 0.14-0.78).

A convenient one-pot completely stereoselective synthesis of trans-4-Hydroxystilbenes and its derivatives and X-ray structure of its precursor

The synthesis of E-isomer of 4-Hydroxystilbene and its derivatives 3 by reductive elimination of the carbonyl function in 2-phenyl-1-(4-hydroxyphenyl)ethan-1-one and its derivatives 2 and the X-ray structure of 2a are described.

REGIOSELECTIVITY OF COMPLEXATIONS OF SUBSTITUTED PHENYL BENZOATES AND PHENYL PHENYLACETATES WITH Cr(CO)6

Selectivity of complexation of substituted phenyl benzoates is very low.In most cases, comparable yields of both regioisomeric complexes are isolated.Exception is 4-chlorophenyl ester, where benzoic acid moiety is complexed nearly exclusively.Very high regioselectivity of complexation was observed with substituted phenyl phenylacetates.The substituent of substituted phenols has not any effect on the complexation, and only phenylacetic acid moiety is complexed.This observation supports the recently proposed mechanism of the catalytic activity of the esters at arene complexation.

A REEXAMINATION OF THE RETRO-FRIES REARRANGEMENT OF SOME o-HYDROXYKETONES

The retro-Fries rearrangement, catalyzed by protic and Lewis acids, was studied for some o-hydroxyketones.The results are consistent with the mechanism of an heterolytic cleavage and rearrangement.It appears that, in general, Lewis acids do not induce the retro-Fries rearrangement of o-hydroxyketones.However, in certain cases, it may be brought about the presence of a protic acid generated in situ, from a solvent-catalyst interaction.