122080-99-3

Basic information

• Product Name: 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one
• Synonyms: 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one;3-Tosyl-3-azabicyclo[3.2.0]heptan-6-one;3-(Toluene-4-sulfonyl)-3-aza-bicyclo[3.2.0]heptan-6-one;Cis-3-Tosyl-3-Azabicyclo[3.2.0]Heptan-6-One
• CAS NO: 122080-99-3
• Molecular Formula: C₁₃H₁₅NO₃S
• Molecular Weight: 265.3281
• Mol File: 122080-99-3.mol

Chemical Properties

• Boiling Point: 437.5±55.0 °C(Predicted)
• Appearance: /
• Density: 1.351±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: -5.91±0.20(Predicted)
• CAS DataBase Reference: 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one(122080-99-3)
• EPA Substance Registry System: 3-(4-Methylbenzenesulfonyl)-3- azabicyclo[3.2.0]heptan-6-one(122080-99-3)

Safety Data

• Hazardous Substances Data: 122080-99-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
3-(4-Methylbenzenesulfonyl)-3-azabicyclo[3.2.0]heptan-6-one is used as a building block in pharmaceutical research for its unique structure and reactivity. It aids in the development of novel drugs and therapeutic agents, enhancing the discovery of new treatments for various diseases and conditions.
Used in Organic Synthesis:
In the field of organic synthesis, 3-(4-Methylbenzenesulfonyl)-3-azabicyclo[3.2.0]heptan-6-one serves as a key intermediate, enabling the synthesis of complex organic molecules. Its unique reactivity allows for the formation of diverse chemical products, contributing to the advancement of organic chemistry.
Used as an Enzyme Inhibitor:
3-(4-Methylbenzenesulfonyl)-3-azabicyclo[3.2.0]heptan-6-one has been studied for its potential as an enzyme inhibitor. Its ability to inhibit specific enzymes can be utilized in the development of targeted therapies for various diseases, providing a promising avenue for drug discovery and treatment.
Used in Drug Development:
3-(4-Methylbenzenesulfonyl)-3-
azabicyclo[3.2.0]heptan-6-one's potential pharmacological properties make it a valuable asset in drug development. Researchers can leverage its unique structure and reactivity to design and synthesize new drug candidates, potentially leading to the creation of innovative treatments for a wide range of medical conditions.

Upstream product

• 122080-91-5 3-{[(4-methylphenyl)sulfonyl]-N-(prop-2-en-1-yl)amino}-1-pyrrolidinylpropan-1-one 
• 98-59-9 p-toluenesulfonyl chloride 
• 42908-33-8 3-{[(4-methylphenyl)sulfonyl]amino}propanoic acid 
• 122081-15-6 3-{[(4-methylphenyl)sulfonyl]amino}-1-pyrrolidinylpropan-1-one 
• 61341-03-5 N-(toluene-4-sulfonyl)-β-alanyl chloride 

Downstream Products

• 663172-78-9 tert-butyl 6-hydroxy-3-azabicyclo[3.2.0]heptane-3-carboxylate 

Relevant articles and documents

TRICYCLIC GYRASE INHIBITORS

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.

Intramolecular [2 + 2] cycloadditions of keteniminium salts derived from α- and β-amino acids. A route to azabicyclic ketones

Unsaturated N-tosylaminoketeniminium salts generated in situ from α- and β-aminoamides readily underwent intramolecular [2 + 2]cycloadditions to give azabicyclic ketones in good yields.