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CAS

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123622-36-6

FMOC-GLU(OBZL)-CL, also known as 9-fluorenylmethoxycarbonyl-L-glutamic acid (2-benzyloxy-4-methylphenyl)methyl ester hydrochloride, is a chemical compound used in the synthesis of peptidomimetics. It is a protected amino acid derivative that plays a crucial role in the solid-phase synthesis of these bioactive molecules.

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  • Pentanoic acid,5-chloro-4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-5-oxo-, phenylmethylester, (4S)- (9CI)

    Cas No: 123622-36-6

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  • 123622-36-6 Structure

  • Basic information

    1. Product Name: FMOC-GLU(OBZL)-CL
    2. Synonyms: FMOC-L-GLUTAMYL CHLORIDE GAMMA-BENZYL ESTER;FMOC-GLU(OBZL)-CL;FMOC-GAMMA-BENZYL ESTER-L-GLUTAMYL CHLORIDE;NALPHA-9-Fluorenylmethoxycarbonyl-L-glutamyl chloride GAMMA-benzyl es;Fmoc-L-glutamyl chloride -benzyl ester;Fmoc-L-Glu(OBzl)-Cl;Fmoc-γ-benzyl ester-L-glutamyl chloride≥ 95%;benzyl (4S)-5-chloro-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxopentanoate
    3. CAS NO:123622-36-6
    4. Molecular Formula: C27H24ClNO5
    5. Molecular Weight: 477.94
    6. EINECS: N/A
    7. Product Categories: Amino Acids
    8. Mol File: 123622-36-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Store at 0°C
    8. Solubility: N/A
    9. CAS DataBase Reference: FMOC-GLU(OBZL)-CL(CAS DataBase Reference)
    10. NIST Chemistry Reference: FMOC-GLU(OBZL)-CL(123622-36-6)
    11. EPA Substance Registry System: FMOC-GLU(OBZL)-CL(123622-36-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 123622-36-6(Hazardous Substances Data)

123622-36-6 Usage

Uses

Used in Pharmaceutical Industry:
FMOC-GLU(OBZL)-CL is used as a reactant in the solid-phase synthesis of oxazole-containing peptidomimetics for their potential therapeutic applications. These peptidomimetics are designed to mimic the structure and function of natural peptides, offering improved stability, bioavailability, and target specificity. The incorporation of oxazole rings in these molecules can lead to enhanced biological activity and selectivity, making them valuable candidates for drug discovery and development.

Check Digit Verification of cas no

The CAS Registry Mumber 123622-36-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,6,2 and 2 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 123622-36:
(8*1)+(7*2)+(6*3)+(5*6)+(4*2)+(3*2)+(2*3)+(1*6)=96
96 % 10 = 6
So 123622-36-6 is a valid CAS Registry Number.

123622-36-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name FMOC-GLU(OBZL)-CL

1.2 Other means of identification

Product number -
Other names Fmoc-L-glutamyl chloride-benzyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:123622-36-6 SDS

123622-36-6Relevant articles and documents

Rapid Continous Peptide Synthesis via FMOC Amino Acid Chloride Coupling and 4-(Aminomethyl)piperidine Deblocking

Beyermann, Michael,Bienert, Michael,Niedrich, Hartmut,Carpino, Louis A.,Sadat-Aalaee, Dean

, p. 721 - 728 (2007/10/02)

The recently described FMOC/4-AMP technique for rapid continous solution synthesis of peptides involving coupling by crystalline FMOC amino acid chlorides and deblocking via 4-(aminomethyl)piperidine (4-AMP) has been extended to the synthesis of a varied

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