123629-53-8

Usage

Uses

Used in Organic Synthesis:
1,3-DIIODO-5-FLUOROBENZENE is used as a reagent for the synthesis of various fluorinated organic molecules, leveraging its unique structure to facilitate chemical reactions that yield desired products with specific properties.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1,3-DIIODO-5-FLUOROBENZENE serves as an intermediate in the manufacturing process of certain drugs. Its role is crucial for the development of new pharmaceuticals with potential therapeutic benefits.
Used in Agrochemical Production:
Similarly, in agrochemicals, 1,3-DIIODO-5-FLUOROBENZENE is utilized as an intermediate, contributing to the creation of compounds that are used in agricultural applications to protect crops and enhance yields.
Used in Materials Science:
1,3-DIIODO-5-FLUOROBENZENE also finds application in materials science, where it is studied for its potential properties in organic electronic devices. Its unique combination of halogens and aromatic structure makes it a candidate for research in advancing material technologies.
Overall, 1,3-DIIODO-5-FLUOROBENZENE is a multifaceted chemical compound with applications spanning across different industries, from pharmaceuticals and agrochemicals to materials science and organic electronics, highlighting its importance in the development of innovative molecules and technologies.

Upstream product

• 618-87-1 3, 5-dinitroaniline 
• 88162-54-3 4-fluoro-2,6-diiodoaniline 
• 1509937-21-6 5-fluoro-1,2,3-triiodobenzene 
• 371-40-4 4-fluoroaniline 
• 1048025-59-7 4-fluoro-2,6-diiodobenzoic acid 
• 456-22-4 4-Fluorobenzoic acid 

Relevant academic research and scientific papers

A simple and efficient two-step synthesis of 1,2,3-triiodoarenes via consecutive C-H iodination/ipso-Iododecarboxylation strategy: A potential application towards Ortho-diiodoarenes by Regioselective metal-iodine exchange reaction

A general, robust, and efficient method for the conversion of benzoic acids to 1,2,3-triiodoarenes and 1,2,3-trihaloarenes via a two-step synthesis is reported. Commercially available benzoic acids were used that can allow the reactions to be performed on multi-gram scales with good-to-excellent yields. This report discloses a practical method for the synthesis of 1,2,3-triiodoarenes and 1,2,3-trihaloarenes that is general in scope, scalable, and easy to workup and purify. A potential application of the target compounds as precursors for novel regioselective metal-iodine exchange reaction of 1,2,3-triiodoarenes was also demonstrated. It provided ortho-diiodoaryl derivatives in a high regioselective fashion that are useful intermediates in synthesis and indeed are hard to synthesize by any other means.

A mild and convenient synthesis of 1,2,3-triiodoarenes via consecutive iodination/diazotization/iodination strategy

A mild and convenient synthesis of 1,2,3-triiodoarenes has been developed. This method consists of two steps which can be performed on multigram scale with moderate to excellent yields. This report discloses a practical synthesis of 1,2,3-triiodoarenes and 1,2,3-trihaloarenes that is general in scope, operationally simple, scalable, and is easy to workup and to purify. We also report the first regioselective transmetalation reaction of 1,2,3-triiodoarenes to provide ortho-diiodoaryl derivatives, which are useful building blocks and indeed are hard to make by other means. CSIRO 2013.