1-Fluoro-3,5-diiodobenzene

Base Information

Chemical Name:1-Fluoro-3,5-diiodobenzene
CAS No.:123629-53-8
Molecular Formula:C6H3 F I2
Molecular Weight:347.897
Hs Code.:
DSSTox Substance ID:DTXSID20697870
Wikidata:Q82627897
Mol file:123629-53-8.mol

Synonyms:1-Fluoro-3,5-diiodobenzene;123629-53-8;1,3-DIIODO-5-FLUOROBENZENE;Benzene, 1-fluoro-3,5-diiodo-;Benzene,1-fluoro-3,5-diiodo-;3,5-diiodofluorobenzene;SCHEMBL18335412;DTXSID20697870;AKOS015910453

Suppliers and Price of 1-Fluoro-3,5-diiodobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,3-DIIODO-5-FLUOROBENZENE 98.00%
5G
$ 1559.25

Alichem
1,3-Diiodo-5-fluorobenzene
1g
$ 1666.00

Total 12 raw suppliers

Chemical Property of 1-Fluoro-3,5-diiodobenzene

Chemical Property:

PSA：0.00000
LogP:3.03490
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:347.83082
Heavy Atom Count:9
Complexity:87.1

Purity/Quality:

99% ^*data from raw suppliers

1,3-DIIODO-5-FLUOROBENZENE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C=C1I)I)F

Technology Process of 1-Fluoro-3,5-diiodobenzene

There total 6 articles about 1-Fluoro-3,5-diiodobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1509937-21-6
5-fluoro-1,2,3-triiodobenzene

: 123629-53-8
3.5-Diiod-fluorbenzol

Guidance literature:: 5-fluoro-1,2,3-triiodobenzene; With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃; for 1h;

With ethanol; In tetrahydrofuran; for 24h; regioselective reaction;
DOI:10.1071/CH13324

Reference yield:

: 371-40-4
4-fluoroaniline

: 123629-53-8
3.5-Diiod-fluorbenzol

Guidance literature:: Multi-step reaction with 3 steps

1.1: iodine; silver sulfate / ethanol / 24 h / 25 °C

2.1: hydrogenchloride / diethyl ether; water / 0 °C

2.2: 0.17 h / 5 °C

2.3: 50 - 80 °C

3.1: tert.-butyl lithium / tetrahydrofuran / 1 h / -78 °C

3.2: 24 h

With hydrogenchloride; iodine; tert.-butyl lithium; silver sulfate; In tetrahydrofuran; diethyl ether; ethanol; water; 2.2: |Sandmeyer Reaction / 2.3: |Sandmeyer Reaction;
DOI:10.1071/CH13324

Reference yield:

: 88162-54-3
4-fluoro-2,6-diiodoaniline

: 123629-53-8
3.5-Diiod-fluorbenzol

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / diethyl ether; water / 0 °C

1.2: 0.17 h / 5 °C

1.3: 50 - 80 °C

2.1: tert.-butyl lithium / tetrahydrofuran / 1 h / -78 °C

2.2: 24 h

With hydrogenchloride; tert.-butyl lithium; In tetrahydrofuran; diethyl ether; water; 1.2: |Sandmeyer Reaction / 1.3: |Sandmeyer Reaction;
DOI:10.1071/CH13324