1242336-94-2

Basic information

• Product Name: 2,5-dichlorobenzoic acid Methyl ester
• Synonyms: 2,5-Dichlorobenzoic acid methyl ester radical ion
• CAS NO: 1242336-94-2
• Molecular Formula: C8H6Cl2O2
• Molecular Weight: 205
• Mol File: 1242336-94-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-dichlorobenzoic acid Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dichlorobenzoic acid Methyl ester(1242336-94-2)
• EPA Substance Registry System: 2,5-dichlorobenzoic acid Methyl ester(1242336-94-2)

Safety Data

• Hazardous Substances Data: 1242336-94-2(Hazardous Substances Data)

Usage

Type of Compound

A derivative of benzoic acid.

Key Features

Contains two chlorine atoms attached to the benzene ring.

Common Uses

Production of agrochemicals and pharmaceuticals.

Functionality

Often employed as an intermediate in the synthesis of herbicides, insecticides, and fungicides.

Effectiveness

Inhibits the growth of unwanted plant species and pests.

Additional Uses

Utilized in the pharmaceutical industry for the development of drugs and pharmaceutical products.

Safety Precautions

Can be harmful if ingested or inhaled, and may irritate the skin and eyes upon contact. Requires careful handling.

Upstream product

• 67-56-1 methanol 
• 119267-70-8 Acetic acid 2-(2,5-dichloro-phenyl)-2-oxo-ethyl ester 
• 35112-27-7 ethyl 2,5-dichlorobenzoate 
• 17287-03-5 trimethylsulphonium hydroxide 
• 50-79-3 2,5-dichlorobenzoic acid 
• 65-85-0 benzoic acid 
• 201230-82-2 carbon monoxide 
• 120-82-1 1,2,4-Trichlorobenzene 

Downstream Products

• 936479-44-6 methyl 5-chloro-2-(trimethylstannanyl)benzoate 
• 99585-13-4 methyl 2-methyl-5-chlorobenzoate 

Relevant articles and documents

Chemoselectivity of cobalt-catalysed carbonylation-A reliable platform for the synthesis of fluorinated benzoic acids

The cobalt-catalysed methoxycarbonylation of polysubstituted bromo,fluoro- and chloro,fluorobenzenes and 1,2,4-trichlorobenzene with emphasis on the chemo- and regio-selectivity of the reaction is described. The structures of isolated products of 1,4-dichloro-2-fluorobenzene carbonylation were determined by single-crystal X-ray diffraction. The fact that the fluorine substituents in the studied compounds remain intact indicates in favor of the anion-radical activation of aryl halides by a cobalt catalyst. For the first time, a universal method of preparation of the various fluorobenzoic acid derivatives from available raw materials with a good yield has been elaborated.

COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE

A composition for an organic optoelectronic device, an organic optoelectronic device, and a display device, the composition including a first compound represented by Chemical Formula 1 and a second compound represented by a combination of Chemical Formula 2 and Chemical Formula 3:

Preparation method of dicamba

The invention relates to a preparation method of dicamba. The method comprises the following steps: preparing 2, 5-dichlorobenzoic acid as a starting raw material; further esterifying with methyl alcohol in an acidic condition; processing to obtain a product; further substituting with bromine under the effect of aluminum tribromide; reacting the obtained product with methyl alcohol under the effect of a catalyst; processing; and further hydrolyzing the obtained product to obtain the final product, namely dicamba. Compared with a traditional synthesizing method, the method has the advantages that few synthesizing steps are performed; the reaction process is simple; the reaction temperature is low; the operation safety is improved; the reaction processing in each step is simple, so that thereaction can be conveniently carried out; and the yield is high.

ANTI-HCMV COMPOSITIONS AND METHODS

This document relates to compounds useful as agents for preventing or treating human cytomegalovirus (HCMV) infections.

Electroreduction of organic compounds, 36 [1]. Electroreduction of chlorinated methyl benzoates

The preparative electroreduction of the three methyl monochlorobenzoates, the six methyl dichlorobenzoates, and methyl 2,3,4-trichlorobenzoate in different solvent-supporting electrolytes (SSE) was studied. The rate of the dechlorination, which is the main reaction, is dependent on the substitution pattern. Pronounced regioselectivity is therefore observed in case of the oligochloro derivatives. Hydrogenation of the benzene ring and reduction of the methoxycarbonyl group with formation of a hydroxymethyl group are observed as side-reactions. Quantum chemical calculations on the reaction mechanism were performed. The theoretical results are in accordance with the experimental observations.

Natural formation of chlorobenzoic acids (CBA) and distinction between PCB-degraded CBA

Mono- and dichlorobenzoic acid (CBA) could be found in samples of remote bog pond water and sediment. The 2,4-CBA always had the highest concentrations. In bog water samples the concentrations ranged between 0.11 and 0.48 μg/l. Besides 2,4-CBA most only 2,5-CBA could be found as dichlorobenzoic acid. In all samples we could detect also trichloroacetic acid (TCAA). The TCAA concentrations correlate with the CBA concentrations. As TCAA is known as a naturally produced organohalogen, this correlation can be seen as an indication to a natural formation of CBA. A confirmation of this presumption is our detection CBA in a reaction of benzoic acid with the chlorinating enzyme chloroperoxidase (CPO).

CLEAVAGE OF THE PHENACYL ESTERS OF CARBOXYLIC AND THIOCARBOXYLIC ACIDS BY METAL ALKOXIDES

During the cleavage of phenacyl esters with general formula XC6H4COCH2OCOR by metal alkoxides in alcohols and in ether-alcohol solutions the acids, esters, and ethers are formed as a result of cleavage of the C-C bond.The solvent participates in the formation of the ether and gives rise to transesterification of RCOOCH3 with catalytic participation of the metal alkoxide.The reactivity of the phenacyl esters of the thio acids is much higher.Before dissociation the esters of substituted benzoins C6H5COCH(OCOCH3).C6H4X-4 undergo irreversible rearrangement with the formation of isomeric products.