124555-44-8

Basic information

• Product Name: CIS-3-AMINO-CYCLOHEXANOL HYDROCHLORIDE
• Synonyms: CIS-3-AMINO-CYCLOHEXANOL HYDROCHLORIDE;(1S,3R)-3-Amino-cyclohexanol hydrochloride;(1S,3R)-3-aminocyclohexan-1-ol
• CAS NO: 124555-44-8
• Molecular Formula: C₆H₁₃NO*ClH
• Molecular Weight: 151.636
• Product Categories: organic building block
• Mol File: 124555-44-8.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• Solubility: Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: CIS-3-AMINO-CYCLOHEXANOL HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-3-AMINO-CYCLOHEXANOL HYDROCHLORIDE(124555-44-8)
• EPA Substance Registry System: CIS-3-AMINO-CYCLOHEXANOL HYDROCHLORIDE(124555-44-8)

Safety Data

• Hazardous Substances Data: 124555-44-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
CIS-3-AMINO-CYCLOHEXANOL HYDROCHLORIDE is used as a reactant for the preparation of isoxazole carboxamide compounds. These compounds are potent, soluble, and orally active TRPV1 antagonists and analgesics, making them valuable in the development of new pain management therapies.
In the synthesis of isoxazole carboxamide compounds, CIS-3-AMINO-CYCLOHEXANOL HYDROCHLORIDE plays a crucial role in the formation of the desired molecular structure, which is essential for the biological activity and therapeutic potential of the final product. By incorporating this compound into the synthesis process, researchers can create novel and effective treatments for various types of pain, potentially improving patient outcomes and quality of life.

Upstream product

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• 610302-03-9 tert-butyl N-(3-hydroxycyclohexyl)carbamate 
• 1425253-99-1 C₁₁H₂₁NO₃ 

Relevant articles and documents

TETRACYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS

The present invention relates to Tetracyclic Heterocycle Compounds of Formula (I) and pharmaceutically acceptable salts or prodrug thereof, wherein n, X, Y, Z, R1, R2, and R3 are as defined herein. The present invention also relates to compositions comprising at least one Tetracyclic Heterocycle Compound, and methods of using the Tetracyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.

Stereocontrolled Preparation of Cyclohexane Amino Alcohols Utilising a Modified Mitsunobu Reaction

A method for the introduction of amino groups into aliphatic systems is described.Cyclohex-2-enol reacts with aromatic diacylamines under Mitsunobu reaction conditions to give either N-alkylated or O-alkylated products in a controlled, predictable manner.