125292-98-0Relevant articles and documents
Synthetic method of pilosin B and intermediate pseudomonophenols thereof
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, (2021/11/26)
The invention discloses a method for synthesizing pilosin B and intermediate pseudomonophenols thereof. The synthesis method of the pseudo-sheep equol comprises the step E. Step F and Step g. The synthetic method of the pilosin B provided by the invention is prepared by the following steps H, step J, preparation of the pseudomonophenols synthesized by the above method, and preparation of the pseudomonophenols synthesized by the method in step I. In step E, the novel amino protecting reagent with good reaction with the phenolic hydroxyl group is used as a protecting reagent, the phenol hydroxyl group of each intermediate in the intermediate molecule fragment a synthesis process is selectively protected, the reagent types are reduced and the use of toxic reagents such as benzyl chloride and the like is avoided.
Preparation method of phloroglucinol derivative and intermediate
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Page/Page column 9-11, (2018/07/30)
The invention discloses a preparation method of a phloroglucinol derivative and an intermediate. The preparation method of the phloroglucinol derivative includes the step: performing reaction on a compound 1 and a compound 3 under the action of lewis acid in an aprotic organic solvent to obtain the phloroglucinol derivative. The phloroglucinol derivative is provided with an agrimophol B, the preparation method is simple, easy to operate, mild in reaction condition and high in synthetic yield, chromatographic column separation is omitted, synthetic cost is reduced, and industrial mass production is facilitated.