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(R)-(-)-Agrimol B is a natural organic compound derived from the leaves of the plant Eupatorium chinense, also known as Chinese thoroughwort. It is a sesquiterpenoid lactone with a bicyclic lactone ring system featuring a trans-fused five-six-membered ring and a conjugated α,β-unsaturated carbonyl group. (R)-(-)-Agrimol B has demonstrated various biological activities, such as anti-inflammatory, antioxidant, and cytotoxic effects, making it a potential therapeutic agent for treating inflammatory conditions and cancer.

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  • 125292-98-0 Structure
  • Basic information

    1. Product Name: (R)-(-)-Agrimol B
    2. Synonyms: (R)-(-)-Agrimol B;(R)-1-[3,5-Bis[[2,6-dihydroxy-4-methoxy-3-methyl-5-(1-oxobutyl)phenyl]methyl]-2,4,6-trihydroxyphenyl]-2-methyl-1-butanone
    3. CAS NO:125292-98-0
    4. Molecular Formula: C37H46O12
    5. Molecular Weight: 682.75
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 125292-98-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-(-)-Agrimol B(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-(-)-Agrimol B(125292-98-0)
    11. EPA Substance Registry System: (R)-(-)-Agrimol B(125292-98-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 125292-98-0(Hazardous Substances Data)

125292-98-0 Usage

Uses

Used in Pharmaceutical Industry:
(R)-(-)-Agrimol B is used as a therapeutic agent for its anti-inflammatory properties, helping in the treatment of various inflammatory conditions. Its antioxidant effects also contribute to its potential use in this application.
Used in Oncology:
(R)-(-)-Agrimol B is used as a cytotoxic agent for its potential application in cancer treatment. Its significant pharmacological properties make it a promising candidate for the development of novel pharmaceutical drugs targeting cancer cells.
Used in Drug Development:
(R)-(-)-Agrimol B is used as a lead compound in the development of new pharmaceutical drugs due to its diverse biological activities and potential therapeutic applications in treating inflammatory conditions and cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 125292-98-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,2,9 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 125292-98:
(8*1)+(7*2)+(6*5)+(5*2)+(4*9)+(3*2)+(2*9)+(1*8)=130
130 % 10 = 0
So 125292-98-0 is a valid CAS Registry Number.

125292-98-0Downstream Products

125292-98-0Relevant articles and documents

Synthetic method of pilosin B and intermediate pseudomonophenols thereof

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, (2021/11/26)

The invention discloses a method for synthesizing pilosin B and intermediate pseudomonophenols thereof. The synthesis method of the pseudo-sheep equol comprises the step E. Step F and Step g. The synthetic method of the pilosin B provided by the invention is prepared by the following steps H, step J, preparation of the pseudomonophenols synthesized by the above method, and preparation of the pseudomonophenols synthesized by the method in step I. In step E, the novel amino protecting reagent with good reaction with the phenolic hydroxyl group is used as a protecting reagent, the phenol hydroxyl group of each intermediate in the intermediate molecule fragment a synthesis process is selectively protected, the reagent types are reduced and the use of toxic reagents such as benzyl chloride and the like is avoided.

Preparation method of phloroglucinol derivative and intermediate

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Page/Page column 9-11, (2018/07/30)

The invention discloses a preparation method of a phloroglucinol derivative and an intermediate. The preparation method of the phloroglucinol derivative includes the step: performing reaction on a compound 1 and a compound 3 under the action of lewis acid in an aprotic organic solvent to obtain the phloroglucinol derivative. The phloroglucinol derivative is provided with an agrimophol B, the preparation method is simple, easy to operate, mild in reaction condition and high in synthetic yield, chromatographic column separation is omitted, synthetic cost is reduced, and industrial mass production is facilitated.

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