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2-([1,1'-BIPHENYL]-4-YLOXY)ETHYLAMINE HYDROCHLORIDE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 125470-84-0 Structure
  • Basic information

    1. Product Name: 2-([1,1'-BIPHENYL]-4-YLOXY)ETHYLAMINE HYDROCHLORIDE
    2. Synonyms: 2-([1,1'-BIPHENYL]-4-YLOXY)ETHYLAMINE HYDROCHLORIDE;[2-(biphenyl-4-yloxy)ethyl]amine hydrochloride;2-(biphenyl-4-yloxy)ethanamine;2-(4-phenylphenoxy)ethanamine;2-(4-phenylphenoxy)ethylamine;ASN 13683383;ZERO/006357;2-([1,1'-biphenyl]-4-yloxy)ethanamine
    3. CAS NO:125470-84-0
    4. Molecular Formula: C14H15NO
    5. Molecular Weight: 249.74
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 125470-84-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 370.1±35.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.072±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 8.67±0.10(Predicted)
    10. CAS DataBase Reference: 2-([1,1'-BIPHENYL]-4-YLOXY)ETHYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-([1,1'-BIPHENYL]-4-YLOXY)ETHYLAMINE HYDROCHLORIDE(125470-84-0)
    12. EPA Substance Registry System: 2-([1,1'-BIPHENYL]-4-YLOXY)ETHYLAMINE HYDROCHLORIDE(125470-84-0)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 125470-84-0(Hazardous Substances Data)

125470-84-0 Usage

Class

Phenylmethylamines

Common use

Precursor in the synthesis of various pharmaceuticals and research chemicals

Physical form

White crystalline powder

Solubility

Soluble in water and ethanol

Applications

Building block for the synthesis of biologically active compounds, reagent in chemical reactions

Stability

Stable and convenient form for use in research and industrial settings

Check Digit Verification of cas no

The CAS Registry Mumber 125470-84-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,4,7 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 125470-84:
(8*1)+(7*2)+(6*5)+(5*4)+(4*7)+(3*0)+(2*8)+(1*4)=120
120 % 10 = 0
So 125470-84-0 is a valid CAS Registry Number.

125470-84-0Downstream Products

125470-84-0Relevant articles and documents

Identification of N-(2-Phenoxyethyl)imidazo[1,2-a]pyridine-3-carboxamides as New Antituberculosis Agents

Wu, Zhaoyang,Lu, Yu,Li, Linhu,Zhao, Rui,Wang, Bin,Lv, Kai,Liu, Mingliang,You, Xuefu

supporting information, p. 1130 - 1133 (2016/12/16)

A series of imidazo[1,2-a]pyridine carboxamides (IPAs) bearing an N-(2-phenoxyethyl) moiety was designed and synthesized as new antitubercular agents. Seven 2,6-dimethyl IPAs demonstrated excellent in vitro activity (MIC: 0.025-0.054 μg/mL) against the drug susceptive H37Rv strain and two clinically isolated multidrug-resistant Mycobacterium tuberculosisstrains. Compound 10j displayed acceptable safety and pharmacokinetic properties, opening a new direction for further development.

Discovery of a new series of 5-HT1A receptor agonists

Franchini, Silvia,Prandi, Adolfo,Sorbi, Claudia,Tait, Annalisa,Baraldi, Annamaria,Angeli, Piero,Buccioni, Michela,Cilia, Antonio,Poggesi, Elena,Fossa, Paola,Brasili, Livio

scheme or table, p. 2017 - 2020 (2010/07/07)

Starting from compounds previously identified as α1-adrenoceptor antagonists that were also found to bind to the 5-HT1A receptor, in an attempt to separate the two activities, a new series of 5-HT1A receptor agonists was identified and shown to have high potency and/or high selectivity. Of these, compound 13, which combines high selectivity (5-HT1A/α1 = 151) and good agonist potency (pD2 = 7.82; Emax = 76), was found to be the most interesting.

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