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1-(4-CHLORO-PHENYL)-5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER is a chemical compound belonging to the pyrazole class, characterized by its molecular formula C13H12ClN3O2. This ethyl ester derivative of 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-3-carboxylic acid is known for its diverse biological activities and potential therapeutic applications.

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  • 126067-52-5 Structure
  • Basic information

    1. Product Name: 1-(4-CHLORO-PHENYL)-5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
    2. Synonyms: 1-(4-CHLORO-PHENYL)-5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER;Ethyl 1-(4-chlorophenyl)-5-Methyl-1H-pyrazole-3-carboxylate
    3. CAS NO:126067-52-5
    4. Molecular Formula: C13H13ClN2O2
    5. Molecular Weight: 264.71
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 126067-52-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 375.3°C at 760 mmHg
    3. Flash Point: 180.8°C
    4. Appearance: /
    5. Density: 1.25g/cm3
    6. Vapor Pressure: 7.85E-06mmHg at 25°C
    7. Refractive Index: 1.583
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: 1-(4-CHLORO-PHENYL)-5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-(4-CHLORO-PHENYL)-5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER(126067-52-5)
    12. EPA Substance Registry System: 1-(4-CHLORO-PHENYL)-5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER(126067-52-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 126067-52-5(Hazardous Substances Data)

126067-52-5 Usage

Uses

Used in Pharmaceutical Industry:
1-(4-CHLORO-PHENYL)-5-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER is used as a potential drug candidate for the treatment of various diseases and conditions. Its application is based on its diverse biological activities and potential therapeutic properties, which make it a promising compound for further research and development in the pharmaceutical field.
Further research and studies are required to fully understand the properties and potential uses of this chemical compound, as it may hold significant value in the development of new treatments and therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 126067-52-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,0,6 and 7 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 126067-52:
(8*1)+(7*2)+(6*6)+(5*0)+(4*6)+(3*7)+(2*5)+(1*2)=115
115 % 10 = 5
So 126067-52-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H13ClN2O2/c1-3-18-13(17)12-8-9(2)16(15-12)11-6-4-10(14)5-7-11/h4-8H,3H2,1-2H3

126067-52-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 1-(4-chlorophenyl)-5-methylpyrazole-3-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:126067-52-5 SDS

126067-52-5Relevant articles and documents

MODULATORS OF THE INTEGRATED STRESS PATHWAY

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Page/Page column 291, (2019/05/22)

Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

MODULATORS OF THE INTEGRATED STRESS PATHWAY

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Page/Page column 357, (2017/12/15)

Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

Optimization of non-ATP competitive CDK/cyclin groove inhibitors through REPLACE-mediated fragment assembly

Liu, Shu,Premnath, Padmavathy Nandha,Bolger, Joshua K.,Perkins, Tracy L.,Kirkland, Lindsay O.,Kontopidis, George,McInnes, Campbell

, p. 1573 - 1582 (2013/04/10)

A major challenge in drug discovery is to develop and improve methods for targeting protein-protein interactions. Further exemplification of the REPLACE (REplacement with Partial Ligand Alternatives through Computational Enrichment) strategy for generatin

Functionalized 4-aminoquinolines by rearrangement of pyrazole N-heterocyclic carbenes

Schmidt, Andreas,Muenster, Niels,Dreger, Andrij

supporting information; experimental part, p. 2790 - 2793 (2010/07/04)

(Figure Presented) Thermal decarboxylation of 1-phenyl pyrazolium-3- carboxylates from the mesomeric betaine class of substances leads to pyrazole-N-heterocyclic carbenes, which immediately rearrange to multiply substituted 4-aminoquinolines (see scheme). These species are of interest for the synthesis of heterocycles and pharmacologically active compounds.

Pyrazole-amides and sulfonamides as sodium channel modulators

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Page/Page column 15, (2010/02/10)

Compounds of the present invention modulate PN3 in mammals and are useful in treating pain in mammals.

Pyrazole-amides and sulfonamides as sodium channel modulators

-

Page 16, (2010/02/09)

Compounds of the present invention modulate PN3 in mammals and are useful in treating pain in mammals.

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