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126257-07-6

H-P-AMINO-D-PHE-OH HCL, also known as 4-Amino-D-phenylalanine Hydrochloride, is an organic compound that serves as a crucial reagent in the synthesis of various pharmaceuticals. It is a derivative of amino acids, specifically D-phenylalanine, with a hydrochloride salt form that enhances its solubility and stability.
Used in Pharmaceutical Industry:
H-P-AMINO-D-PHE-OH HCL is used as a reagent for the synthesis of D-Melphalan (M216915), an isomer of Melphalan (M216900). D-Melphalan is an antineoplastic agent, which means it has the ability to inhibit the growth and proliferation of cancer cells. This makes H-P-AMINO-D-PHE-OH HCL an essential component in the development of cancer treatments.
In the synthesis of D-Melphalan, H-P-AMINO-D-PHE-OH HCL plays a critical role as it contributes to the formation of the final product, which possesses antineoplastic properties. This application highlights the importance of H-P-AMINO-D-PHE-OH HCL in advancing cancer research and therapeutics, ultimately aiming to improve patient outcomes and survival rates.

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  • 126257-07-6 Structure

  • Basic information

    1. Product Name: H-P-AMINO-D-PHE-OH HCL
    2. Synonyms: H-D-PHE(4-NH2)-OH HCL;H-P-AMINO-D-PHE-OH HCL;(4-AMINO)-D-PHENYLALANINE HYDROCHLORIDE;P-AMINO-D-PHENYLALANINE HCL;P-AMINO-D-PHENYLALANINE HYDROCHLORIDE;H-p-Amino-D-Phe-OH;(R)-2-amino-3-(4-aminophenyl)propionic acid hydrochloride;D-Phe(4-NH2)-OH·HCl
    3. CAS NO:126257-07-6
    4. Molecular Formula: C9H12N2O2*2ClH
    5. Molecular Weight: 216.66
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 126257-07-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /white powder
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: H2O: 20 mg/mL, soluble
    9. CAS DataBase Reference: H-P-AMINO-D-PHE-OH HCL(CAS DataBase Reference)
    10. NIST Chemistry Reference: H-P-AMINO-D-PHE-OH HCL(126257-07-6)
    11. EPA Substance Registry System: H-P-AMINO-D-PHE-OH HCL(126257-07-6)

  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 126257-07-6(Hazardous Substances Data)

126257-07-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 126257-07-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,2,5 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 126257-07:
(8*1)+(7*2)+(6*6)+(5*2)+(4*5)+(3*7)+(2*0)+(1*7)=116
116 % 10 = 6
So 126257-07-6 is a valid CAS Registry Number.

126257-07-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Amino-L-phenylalanine hydrochloride (1:1)

1.2 Other means of identification

Product number -
Other names L-p-aminophenylalanine dihydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:126257-07-6 SDS

126257-07-6Downstream Products

126257-07-6Relevant articles and documents

Biosynthesis of the Antibiotic Obafluorin from D-Glucose and p-Aminophenylalanine in Pseudomonas fluorescens

Herbert, Richard B.,Knaggs, Andrew R.

, p. 103 - 108 (2007/10/02)

The separate units which are used to construct the antibiotic obafluorin 1 in Pseudomonas fluorescens are defined by the results of D-glucose incorporation.A key intermediate in the biosynthesis of 1 is established to be L-p-aminophenylalanine 8; L-phenylanaline and L-p-nitrophenylalanine are very poor precursors.Results similar to those for obafluorin are obtained for p-nitrophenylacetic acid 20 which along with derivative 4 and 2-(4-nitrophenyl)ethanol 21 are identified as new metabolites of P. fluorescens.Deuteriated samples of 20, 22 and 23 are notprecursors for obafluorin 1. -p-aminophenylalanine 18 is incorporated into 1 with complete loss of deuterium from C-2 but retention of the deuterium present in both diastereotopic positions on C-3.

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