1268241-74-2

Basic information

• Product Name: 2,4-dichloropyrido[3',2':4,5]furo[3,2-d]pyrimidine
• Synonyms: 2,4-dichloropyrido[3',2':4,5]furo[3,2-d]pyrimidine
• CAS NO: 1268241-74-2
• Molecular Formula: C9H3Cl2N3O
• Molecular Weight: 240.04562
• Mol File: 1268241-74-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-dichloropyrido[3',2':4,5]furo[3,2-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dichloropyrido[3',2':4,5]furo[3,2-d]pyrimidine(1268241-74-2)
• EPA Substance Registry System: 2,4-dichloropyrido[3',2':4,5]furo[3,2-d]pyrimidine(1268241-74-2)

Safety Data

• Hazardous Substances Data: 1268241-74-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,4-dichloropyrido[3',2':4,5]furo[3,2-d]pyrimidine is used as a key intermediate in the synthesis of various pharmaceuticals for its potential biological activity. It is being studied for its potential as an anti-cancer agent, where it may target and inhibit the growth of cancer cells, offering a new avenue for cancer treatment.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-dichloropyrido[3',2':4,5]furo[3,2-d]pyrimidine is utilized as a precursor in the development of agrochemicals. Its potential biological activity makes it a candidate for the creation of new pesticides or herbicides, contributing to more effective crop protection strategies.
Used in Anti-inflammatory Applications:
2,4-dichloropyrido[3',2':4,5]furo[3,2-d]pyrimidine is also being explored for its potential as an anti-inflammatory agent. It may be used to develop medications that help reduce inflammation and alleviate symptoms associated with various inflammatory conditions.
Used in Disease Treatment:
Furthermore, this compound is under investigation for its role as an inhibitor in the treatment of certain diseases. Its specific inhibitory properties could be harnessed to regulate biological processes or pathways, offering new therapeutic approaches for disease management.
While the exact uses and applications of 2,4-dichloropyrido[3',2':4,5]furo[3,2-d]pyrimidine are still being researched and developed, its presence in the synthesis of pharmaceuticals and agrochemicals highlights its potential impact on both human health and agricultural practices.

Upstream product

• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 371945-06-1 3-amino-furo[2,3-b]pyridine-2-carboxylic acid ethyl ester 
• 1235181-59-5 pyrido[3',2':4,5]furo[3,2-d]pyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

FUSED PYRIMIDINES AS ISOFORM SELECTIVE PHOSPHOINOSITIDE-3-KINASE-ALPHA INHIBITORS AND PROCESS FOR PREPARATION THEREOF

The present invention relates to fused pyrimidines of formulae I and II wherein, R1, R2 are as herein described. The present invention particularly relates to isoform selective PI3Kα inhibition and their medicinal use as anticancer agents.

TRICYCLIC HETEROCYCLIC COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE INHIBITORS

Compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein: W is O, N-H, N-(C1-C10 alkyl) or S; each X is independently CH or N; R1 is a 5 to 7-membered saturated or unsaturated, optionally substituted heterocycle containing at least 1 heteroatom selected from N or O; R2 is (LQ)mY; and each R3 is independently H, C1-C10 alkyl, aryl or heteroaryl, are surprisingly found to be inhibitors of PI3K-p110δ, and therefore have utility in therapy.