126827-25-6

Basic information

• Product Name: BUTTPARK 59\40-15
• Synonyms: BUTTPARK 59\40-15;methyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
• CAS NO: 126827-25-6
• Molecular Formula: C₁₃H₁₄N₂O₂S
• Molecular Weight: 262.33
• Mol File: 126827-25-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BUTTPARK 59\40-15(CAS DataBase Reference)
• NIST Chemistry Reference: BUTTPARK 59\40-15(126827-25-6)
• EPA Substance Registry System: BUTTPARK 59\40-15(126827-25-6)

Safety Data

• Hazardous Substances Data: 126827-25-6(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 100-52-7 benzaldehyde 
• 17356-08-0 thiourea 
• 1147550-11-5 ammonium thiocyanate 
• 105-45-3 acetoacetic acid methyl ester 
• 123-54-6 acetylacetone 

Downstream Products

• 113697-46-4 2-Methylmercapto-5,6-dimethyl-4-phenylpyrimidine 
• 126827-40-5 methyl 4-methyl-2-(methylthio)-6-phenyl-1,6-dihydropyrimidine-5-carboxylate 
• 126827-40-5 methyl 6-methyl-2-(methylthio)-4-phenyl-1,4-dihydropyrimidine-5-carboxylate 
• 126827-29-0 methyl 1,4-dimethyl-2-(methylthio)-6-phenyl-1,6-dihydropyrimidine-5-carboxylate 
• 1619238-01-5 methyl 4-methyl-2-(methylthio)-6-phenylpyrimidine-5-carboxylate 
• 1227077-10-2 methyl 4-methyl-6-phenyl-2-(phenylethynyl)pyrimidine-5-carboxylate 
• 80742-16-1 methyl 4-methyl-2,6-diphenylpyrimidine-5-carboxylate 
• 1606128-32-8 dimethyl 2,2'-disulfanediylbis(4-methyl-6-phenylpyrimidine-5-carboxylate) 
• 126827-27-8 2-methylthio-4-phenyl-5-methoxycarbonyl-6-methyl-1,2,3,4-tetrahydropyrimidinium iodide 
• 1427440-64-9 (2E)-N-hydroxy-5-methoxycarbonyl-6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-iminium chloride 
• 1309220-97-0 methyl (Z)-2-((1-benzylindol-3-yl)methylene)-7-methyl-3-oxo-5-phenylthiazolo[3,2-a]pyrimidine-6-carboxylate 
• 126827-32-5 3-phenyl-4-methoxycarbonyl-5-methyl-7-oxo-8-benzylidene-3H-thiazolidino<3,2-a>pyrimidine 
• 126827-42-7 3-Acetyl-6-methyl-4-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester 

Relevant articles and documents

Decoration of multi-walled carbon nanotubes with NiO nanoparticles and investigation on their catalytic activity to synthesize pyrimidinone heterocycles

A supported carbon material is shown to be a highly efficient, eco-friendly and recyclable solid acid catalyst for the Biginelli reaction of aldehyde, β-ketoester and urea or thiourea under microwave irradiation in the absence of solvent. This method offe

Vegetable oil as a highly effective 100% bio-based alternative solvent for the one-pot multicomponent Biginelli reaction

Multicomponent one-pot Biginelli reactions have been successfully performed using vegetable oil as bio-based, non-toxic, and environmentally friendly solvents. Palm oil was demonstrated to be a highly effective greener solvent as compared to petroleum-bas

Synthesis of 3,4-dihydropyrimidin-2(1H)-one via one-pot Biginelli reaction under solvent-free conditions

Three novel heteropolyanion-based acidic ionic liquids, [TMAPS]H2PMo12O40, [TEAPS]H2PMo12O40, and [TBAPS]H2PMo12O40, were used as efficient catalysts for th

Hetero Diels-Alder reaction: A novel strategy to regioselective synthesis of pyrimido[4,5-d]pyrimidine analogues from Biginelli derivative

A number of potent pyrimido[4,5-d]pyrimidine analogues have been efficiently synthesized by hetero Diels-Alder cycloaddition of 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid methyl ester, a Biginelli compound with N-arylidine-N

Studies on the Biginelli reaction: A mild and selective route to 3,4-dihydropyrimidin-2(1H)-ones via enamine intermediates

L-Proline methyl ester hydrochloride was found to be an effective catalyst for assembling (±)-dihydropyrimidinones under mild conditions. Mechanistic insights into the useful selectivity elements of this amine-catalyzed process are also reported.

Niobium Oxides as Heterogeneous Catalysts for Biginelli Multicomponent Reaction

This study reports a simple, reusable, and recoverable niobium-based heterogeneous catalysts for Biginelli multicomponent reactions. Different methods of catalysts preparation were investigated. For this purpose, HY-340 (Nb2O5·nH2O) and Nb2O5 were chemica

One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using chloroacetic acid as catalyst

A simple and effective synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives from aldehydes, 1,3-dicarbonyl compounds and urea or thiourea using chloroacetic acid as catalyst under solvent-free conditions is described. Compared with the classical Bigine

Alkylammonium and alkylimidazolium perhaloborates, phosphates, and aluminates as catalysts in the Biginelli reaction

Tri- and tetraalkylammonium, 1,3-dialkylimidazolium, and 1,2,3-trialkylimidazolium salts with BF 4 - , PF 6 - , AlCl 4 - , and Al 2Cl 7 - as counterions catalyze the Biginelli reaction, ensuring preparation of various 3,4-dihydropyrimidin-2(1H)-one and 3,4-dihydropyrimidine-2(1H)-thione derivatives in high yields in the absence of a solvent.

Melamine trisulfonic acid: A new, efficient and recyclable catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones in the absence of solvent

Melamine trisulfonic acid (MTSA) can be used as an efficient and recyclable catalyst for the promotion of the synthesis of 3,4-dihydropyrimidin-2(1H)-ones/ thiones (DHPMs) in the absence of solvent. All reactions were performed at 80 °C in good to high yi

Sulfonic Acid and Ionic Liquid Functionalized Covalent Organic Framework for Efficient Catalysis of the Biginelli Reaction

A quinoline-linked and ionic liquid-decorated covalent organic framework was prepared by incorporation of a multicomponent Povarov reaction and postsynthetic modification. The imidazolium and sulfonic acid-decorated COF-IM-SO3H can be a highly efficient B