127168-89-2

Basic information

• Product Name: B90102
• Synonyms: 2-Benzyl-5-methoxyisoindoline;B90102
• CAS NO: 127168-89-2
• Molecular Formula: C₁₆H₁₇NO
• Molecular Weight: 239.316
• Mol File: 127168-89-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: B90102(CAS DataBase Reference)
• NIST Chemistry Reference: B90102(127168-89-2)
• EPA Substance Registry System: B90102(127168-89-2)

Safety Data

• Hazardous Substances Data: 127168-89-2(Hazardous Substances Data)

Usage

Uses

Used in Paper and Cardboard Manufacturing Industry:
B90102 is used as a surfactant for reducing the surface tension of water, which facilitates better dispersion of dyes and pigments in the paper-making process. This enhances the color uniformity and visual appeal of the final product.
B90102 is also used as a wetting agent to ensure that the paper pulp is evenly and thoroughly coated with the necessary chemicals and additives. This promotes a more consistent and higher-quality paper product.
Furthermore, B90102 is utilized to improve the strength and stability of the paper, contributing to its durability and longevity. This is particularly important for applications where the paper or cardboard needs to withstand physical stress or maintain its integrity over time.

Upstream product

• 1007455-12-0 2-benzyl-5-methoxyisoindoline-1,3-dione 
• 36132-96-4 1,2-bis(bromomethyl)-4-methoxybenzene 
• 100-46-9 benzylamine 
• 28281-76-7 5-methoxyisobenzofuran-1,3-dione 

Downstream Products

• 127168-88-1 5-methoxy-2,3-dihydro-1H-isoindole 
• 676499-52-8 C₁₅H₁₅NO 

Relevant articles and documents

Tri(pentaflurophenyl)borane-catalyzed reduction of cyclic imides with hydrosilanes: Synthesis of pyrrolidines

B(C6F5)3-catalyzed hydrosilylation of cyclic imides afforded an efficient synthetic method of pyrrolidines. In the presence of 5 mol% B(C6F5)3, various aromatic, aliphatic and polycyclic imides were smoothly reduced by PhSiH3 to generate the corresponding pyrrolidines in high yields. The reaction profiles monitored by 1H NMR spectroscopy disclosed the reduction process of cyclic imides and the effect of difference structure of the hydrosilanes on the hydrosilylation.

ISOINDOLE DERIVATIVES

This invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, a process of making these compounds, pharmaceutical compositions containing one or more of these compounds or their salts, and their use for the treatment of schizophrenia, bipolar disorder, or other central nervous system disorders.

Design, synthesis, and evaluation of fused heterocyclic analogs of SCH 58261 as adenosine A2A receptor antagonists

SCH 58261 is a reported adenosine A2A receptor antagonist which is active in rat in vivo models of Parkinson's Disease upon ip administration. However, it has poor selectivity versus the A1 receptor and does not demonstrate oral activity. Quinoline analogs have improved upon the selectivity and pharmacokinetics of SCH 58261, but were difficult to handle due to poor aqueous solubility. We report the design and synthesis of fused heterocyclic analogs of SCH 58261 with aqueous solubility as well as improved A2A receptor binding selectivity and pharmacokinetic properties. In particular, the tetrahydronaphthyridine 4s has excellent A2A receptor in vitro binding affinity and selectivity, is active orally in a rat in vivo model of Parkinson's Disease, and has aqueous solubility of 100 μM at physiological pH.

Structure activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 2

A series of 6-bicycloaryloxynicotinamides were identified as opioid receptor antagonists at mu, kappa, and delta receptors. Compounds in the 6-(2,3,4,5-tetrahydro-1H-benzo[c]azepin-7-yloxy)nicotinamide scaffold exhibited potent in vitro functional antagonism at all three receptors.

Isoindoline derivative

Isoindoline derivatives represented by the formula (I) and their salts are disclosed. STR1 There are many varieties for the compound depending on the types of residues R1 -R9 and X. The compounds can be prepared from quinoline derivatives of the formula (II) and an isoindoline derivatives of the formula (III). The compounds of formula (I) and their salts have excellent antibacterial activities against both gram positive and gram negative microorganisms. They can be used as a medicine, an agrichemical, and a food preservative.