2-Benzyl-5-methoxyisoindoline

Base Information

Chemical Name:2-Benzyl-5-methoxyisoindoline
CAS No.:127168-89-2
Molecular Formula:C16H17NO
Molecular Weight:239.317
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90569459
Wikidata:Q82456614
Mol file:127168-89-2.mol

Synonyms:2-Benzyl-5-methoxyisoindoline;127168-89-2;2-BENZYL-5-METHOXY-1,3-DIHYDROISOINDOLE;2-benzyl-5-methoxy-2,3-dihydro-1h-isoindole;SCHEMBL3693352;DTXSID90569459;IXVDZZDUTXTHTM-UHFFFAOYSA-N;CFA16889;AB6226;MFCD12022623;AKOS016001946;AS-44755;2-Benzyl-5-methoxy-2,3-dihydro-1H-isoindol;A889285

Suppliers and Price of 2-Benzyl-5-methoxyisoindoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
2-benzyl-5-methoxyisoindoline 95
5g
$ 1300.00

Crysdot
2-Benzyl-5-methoxyisoindoline 95+%
1g
$ 455.00

Chemenu
2-Benzyl-5-methoxyisoindoline 95%
1g
$ 430.00

American Custom Chemicals Corporation
2-BENZYL-5-METHOXYISOINDOLINE 95.00%
5MG
$ 498.92

Alichem
2-Benzyl-5-methoxyisoindoline
1g
$ 383.16

aablocks
2-Benzyl-5-methoxyisoindoline 95%
250mg
$ 304.00

Total 10 raw suppliers

Chemical Property of 2-Benzyl-5-methoxyisoindoline

Chemical Property:

PSA：12.47000
LogP:3.14890
Storage Temp.:2-8°C
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:239.131014166
Heavy Atom Count:18
Complexity:262

Purity/Quality:

97% ^*data from raw suppliers

2-benzyl-5-methoxyisoindoline 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(CN(C2)CC3=CC=CC=C3)C=C1

Technology Process of 2-Benzyl-5-methoxyisoindoline

There total 4 articles about 2-Benzyl-5-methoxyisoindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1007455-12-0
2-benzyl-5-methoxyisoindoline-1,3-dione

: 127168-89-2
N-benzylisoindolin-5-yl methyl ether

Guidance literature:: With 1,1,3,3-Tetramethyldisiloxane; tris(pentafluorophenyl)borate; In 1,4-dioxane; at 110 ℃; for 16h; Inert atmosphere; Schlenk technique;
DOI:10.1016/j.tet.2018.01.051

Reference yield: 71.0%

: 36132-96-4
1,2-bis(bromomethyl)-4-methoxybenzene

: 100-46-9
benzylamine

: 127168-89-2
N-benzylisoindolin-5-yl methyl ether

Guidance literature:: With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In toluene;
DOI:10.1016/j.bmcl.2007.10.025

Reference yield:

: 28281-76-7
5-methoxyisobenzofuran-1,3-dione

: 100-46-9
benzylamine

: 127168-89-2
N-benzylisoindolin-5-yl methyl ether

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 3 h / Reflux; Inert atmosphere; Schlenk technique

2: tris(pentafluorophenyl)borate; 1,1,3,3-Tetramethyldisiloxane / 1,4-dioxane / 16 h / 110 °C / Inert atmosphere; Schlenk technique

With 1,1,3,3-Tetramethyldisiloxane; tris(pentafluorophenyl)borate; acetic acid; In 1,4-dioxane;
DOI:10.1016/j.tet.2018.01.051