1294505-32-0Relevant articles and documents
Synthesis of [1,2,3]-triazolo[1,5-a][1,4]benzodiazepines via an unprecedented one-pot Cu-catalyzed azidation-cyclization reaction
Hooyberghs, Geert,De Coster, Hendrik,Vachhani, Dipak D.,Ermolat'Ev, Denis S.,Van Der Eycken, Erik V.
, p. 4331 - 4337 (2013/06/04)
A novel three-step approach leading to [1,2,3]-triazolo[1,5-a][1,4] benzodiazepines in moderate to good yields has been developed. The key step is an unprecedented one-pot Cu-catalyzed azidation-cyclization reaction of ortho-bromobenzylpropargylamines.
Synthesis of functionalized tetrahydroisoquinolines via palladium-catalyzed 6-exo-dig carbocyclization of 2-bromo-N-propargylbenzylamines
Nandakumar,Muralidharan,Perumal
experimental part, p. 1644 - 1648 (2011/04/26)
An efficient twostep synthetic strategy for tetrahydroisoquinolines has been described. The first step involves CuI catalyzed three-component coupling reaction of terminal alkyne, aldehyde and amine that provides the requisite propargyl amine. Regio- and