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2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride is a white crystalline chemical compound that serves as a crucial building block in the synthesis of pharmaceuticals and other organic compounds. As a dihydrochloride salt of the ethyl ester of 2-piperazinecarboxylic acid, it is soluble in water and possesses a molecular weight of 254.19 g/mol. Its pivotal role as an intermediate in pharmaceutical synthesis renders it a significant chemical in the pharmaceutical industry, widely utilized in the production of various medications and healthcare products.

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  • 129798-91-0 Structure
  • Basic information

    1. Product Name: 2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride
    2. Synonyms: 2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride
    3. CAS NO:129798-91-0
    4. Molecular Formula: C7H16Cl2N2O2
    5. Molecular Weight: 231.12014
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 129798-91-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride(129798-91-0)
    11. EPA Substance Registry System: 2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride(129798-91-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 129798-91-0(Hazardous Substances Data)

129798-91-0 Usage

Uses

Used in Pharmaceutical Industry:
2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride is used as a key intermediate for the synthesis of various drugs and pharmaceutical products. Its versatile chemical structure allows for the creation of a wide range of medications, contributing to the development of novel therapeutic agents and enhancing the efficacy of existing ones.
Used in Organic Compound Synthesis:
In the field of organic chemistry, 2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride is employed as a valuable building block for the synthesis of diverse organic compounds. Its reactivity and functional groups enable the formation of complex molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Drug Development:
2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride is utilized as a starting material in drug development, facilitating the design and synthesis of new pharmaceutical agents. Its presence in the synthesis process allows researchers to explore innovative drug candidates with improved pharmacological properties, such as increased potency, selectivity, and reduced side effects.
Used in Medication Production:
As a fundamental component in the production of various medications, 2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride plays a critical role in the healthcare sector. Its incorporation into the manufacturing process of different drugs ensures the availability of essential medicines for the treatment and management of numerous medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 129798-91-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,7,9 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 129798-91:
(8*1)+(7*2)+(6*9)+(5*7)+(4*9)+(3*8)+(2*9)+(1*1)=190
190 % 10 = 0
So 129798-91-0 is a valid CAS Registry Number.

129798-91-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl piperazine-2-carboxylate dihydrochloride

1.2 Other means of identification

Product number -
Other names ethyl piperazine-2-carboxylate,dihydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:129798-91-0 SDS

129798-91-0Downstream Products

129798-91-0Relevant articles and documents

2-carboxyl piperazine linked tacrine-8-amino(hydroxyl) quinoline derivative as well as preparation and application

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Paragraph 0040; 0060; 0064-0066, (2019/08/06)

The invention relates to the technical field of chemical synthesis, and specifically relates to a 2-carboxyl piperazine linked tacrine-8-amino(hydroxyl) quinoline derivative as well as preparation andapplication. The 2-carboxyl piperazine linked tacrine-8-amino(hydroxyl) quinoline derivative is a chemical compound shown in a formula I (the formula I is shown in the description) or a pharmaceutically acceptable salt thereof, and a solvent chemical compound, an enantiomer, a diastereoisomer, a tautomer or a mixture in any proportion of the chemical compound shown in the formula I or the pharmaceutically acceptable salt thereof, and includes a racemic mixture. Confirmed by a pharmacological test, the kind of chemical compound has an inhibiting effect on the activity of acetylcholinesterase(AChE) and butyrylcholinesterase(BuChE), and belongs to a cholinesterase inhibitor; the chemical compound also has an inhibiting effect on self-aggregation of beta-amyloid protein, and has delayed action on hydrolysis of acetylcholine and self-aggregation of the beta-amyloid protein, thereby improving the effect of the acetylcholine on a synapse, and finally realizing the purpose of effectively treating alzheimer's disease (AD).

COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USES AS IDH1 MUTANTS INHIBITORS FOR TREATING CANCERS

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Page/Page column 114, (2013/02/28)

Provided are compounds of formula (I), wherein X, Y, Z, W, V, R2, R3 and m are defined as in the description. Their pharmaceutical compositions and their uses as IDH1 mutants inhibitors for treating cancers are also provided

HETEROCYCLIC AMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS

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Page/Page column 44, (2008/06/13)

Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type or T-type calcium channel activity are disclosed. Specifically, a series of heterocyclic amides are disclosed of the general formula (I) where Z is N or CHNR2 and X is NR2, O, S, S=O or SO2. Among other definitions for R, R1, W and Y, the compounds of formula (1) are further characterized by at least one of W or Y being CR3Ar2 where Ar is an aromatic or heteroaromatic ring (for example, where W or Y is a benzhydryl moiety).

Structure-activity relationships in platelet-activating factor. 12. Synthesis and biological evaluation of platelet-activating factor antagonists with anti-HIV-1 activity

Serradji, Nawal,Martin, Marc,Bensaid, Okkacha,Cisternino, Salvatore,Rousselle, Christophe,Dereuddre-Bosquet, Nathalie,Huet, Jack,Redeuilh, Catherine,Lamouri, Aazdine,Dong, Chang-Zhi,Clayette, Pascal,Scherrmann, Jean-Michel,Dormont, Dominique,Heymans, Fran?oise

, p. 6410 - 6419 (2007/10/03)

The HIV-1 central nervous system infection leads to the onset of neurological impairments called AIDS dementia complex (ADC). PAF plays an important role in this pathology, as it is an HIV-1-induced neurotoxin produced by infected or activated macrophages

Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 1. Synthesis and biological activities of N-benzyl-N'-(arylalkyl)-2-(4',5'-dihydro-1'H-imidazol-2'- yl)piperazines

Rondu, Frédéric,Bihan, Gaelic Le,Wang, Xuan,Lamouri, Aazdine,Touboul, Estera,Dive, Georges,Bellahsene, Tounès,Pfeiffer, Bruno,Renard, Pierre,Guardiola-Lemaitre, Béatrice,Manechez, Dominique,Penicaud, Luc,Ktorza, Alain,Godfroid, Jean-Jacques

, p. 3793 - 3803 (2007/10/03)

The physiopathology of non-insulin-dependent diabetes mellitus is associated with a dysfunction in the regulation of insulin secretion. The α2-adrenoceptors have been reported to be involved in this alteration, although α2-antagonist

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