130569-75-4Relevant articles and documents
Benzothiazole derivatives and medicinal products containing them
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, (2008/06/13)
STR1 Compounds of formula (I), in which R1 is a polyfluoralkoxy, R2 is a sulphur or nitrogen atom substituted by an alkyl radical or a sulfonyl or sulfinyl radical, R3 is a phenyl, benzoyl, --NR4 R5 or piperidinyl-4radical substituted in position 1 by a phenylalkyl radical, R4 is an alkyl radical, R5 is a phenylalkyl radical, n is equal to 1, 2 or 3, m is equal to 0, 1, 2 or 3. The present invention also relates to the salts of said compounds, processes for the preparation of the latter and drugs containing them.
1,2,4-THIADIAZINOBENZOTHIAZOLE: A NEW CYCLIC SULPHENIMINE
Jimonet, Patrick,Audiau, Francois,Barreau, Michel,Mignani, Serge
, p. 2745 - 2752 (2007/10/02)
3,4-Dihydro-8-trifluoromethoxy-1,2,4-thiadiazinobenzothiazole (2) was prepared in five steps from 6-trifluoromethoxy-2-benzothiazolamine (riluzole, 1).The key final step consisted of an original N-S bond forming reaction between unsubstituted imine