Welcome to LookChem.com Sign In|Join Free
  • or

1744-22-5

Post Buying Request

1744-22-5 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
Riluzole
Cas No: 1744-22-5
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
Riluzole Cas 1744-22-5 Research chemicals
Cas No: 1744-22-5
No Data 1 Kilogram 100 Kilogram/Week Kono Chem Co.,Ltd Contact Supplier
High quality Riluzole supplier in China
Cas No: 1744-22-5
No Data No Data No Data Simagchem Corporation Contact Supplier
Riluzole
Cas No: 1744-22-5
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Riluzole
Cas No: 1744-22-5
No Data 1 Kilogram 200 Kilogram/Month HENAN SUNLAKE ENTERPRISE CORPORATION Contact Supplier
Riluzole Manufacturer CAS 1744-22-5 with Purity 99% Made by Pharmaceutical Chemicals
Cas No: 1744-22-5
No Data 10 Gram 10 Metric Ton/Quarter Hubei XinRunde Chemical Co., Ltd Contact Supplier
Factory supply Top quality Riluzole in stock
Cas No: 1744-22-5
No Data 1 Kilogram 1000 Kilogram/Month Shaanxi Mingqi Chemical Co., Ltd Contact Supplier
Riluzole CAS NO.1744-22-5
Cas No: 1744-22-5
No Data 10 Gram 400 Metric Ton/Month Hubei Jusheng Technology Co., Ltd., Contact Supplier
Riluzole CAS:1744-22-5
Cas No: 1744-22-5
No Data 1 Kilogram 100 Kilogram/Day Henan Tianfu Chemical Co., Ltd. Contact Supplier
Riluzole/ LIDE PHARMA- Factory supply / Best price
Cas No: 1744-22-5
No Data No Data 1 LIDE PHARMACEUTICALS LIMITED Contact Supplier

1744-22-5 Usage

Uses

A neuroprotective agent. A glutamate release inhibitor. An anticonvulsant

Uses

Labeled Riluzole, intended for use as an internal standard for the quantification of Riluzole by GC- or LC-mass spectrometry.

Uses

A neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.

Brand name

Rilutek (Sanofi Aventis).

References

https://en.wikipedia.org/wiki/Riluzole
http://www.medicinenet.com/riluzole_oral_tablets/article.htm
https://pubchem.ncbi.nlm.nih.gov/compound/5070#section=Top

Description

Riluzole belongs to the derivative of benzothiazole with neuroprotective, potential anti-depressant and anxiolytic activities, which is used in the treatment of a certain type of nerve disease called amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease). It is effective to delay the onset of ventilator-dependence or tracheostomy in selected patients, slow down the deterioration of this disease and probably prolong survival by approximately two to three months. Besides, studies have proved that riluzole has anti-depressant activity for refractory depression and serves as an anxiolytic in the treatment of obsessive-compulsive disorder and generalized anxiety disorder.
However, riluzole does not cure the ALS and reverse nerve damage or muscle weakness. It is believed to function as an inhibitor of a natural substance called glutamate. It helps protect the nerves in the brain and spinal cord from too much of glutamate which may contribute to the nerve damage. Riluzole is available in both tablet and liquid form. The liquid formulation may be more suitable for patients with swallowing difficulties.

Chemical Properties

White Crystalline Solid

Uses

anticonvulsant, glutamate release inhibitor, anti-ALS

Biological Activity

Novel psychotropic agent with anticonvulsant, hypnotic, anxiolytic, anti-ischemic and anesthetic properties. Riluzole is able to act as a glutamate release inhibitor, blocks voltage-dependent Na + channels and inhibits GABA uptake by striatal synaptosomes.
InChI:InChI=1/C8H5F3N2OS.ClH/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5;/h1-3H,(H2,12,13);1H

1744-22-5 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma (R116)  Riluzole  solid 1744-22-5 R116-500MG 10,459.80CNY Detail
Sigma (R116)  Riluzole  solid 1744-22-5 R116-250MG 6,060.60CNY Detail
Sigma (R116)  Riluzole  solid 1744-22-5 R116-25MG 816.66CNY Detail
USP (1604337)  Riluzole  United States Pharmacopeia (USP) Reference Standard 1744-22-5 1604337-200MG 5,515.38CNY Detail
Alfa Aesar (H61328)  2-Amino-6-(trifluoromethoxy)benzothiazole, 98%    1744-22-5 25g 2329.0CNY Detail
Alfa Aesar (H61328)  2-Amino-6-(trifluoromethoxy)benzothiazole, 98%    1744-22-5 5g 1038.0CNY Detail
TCI America (A2423)  2-Amino-6-(trifluoromethoxy)benzothiazole  >98.0%(HPLC)(T) 1744-22-5 25g 3,980.00CNY Detail
TCI America (A2423)  2-Amino-6-(trifluoromethoxy)benzothiazole  >98.0%(HPLC)(T) 1744-22-5 5g 1,290.00CNY Detail

1744-22-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Amino-6-(trifluoromethoxy)benzo[d]thiazole

1.2 Other means of identification

Product number -
Other names 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1744-22-5 SDS

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields