130627-09-7

Basic information

• Product Name: 2-Propanone,1-[(2-aminobenzoyl)oxy]-(9CI)
• Synonyms: 2-Propanone,1-[(2-aminobenzoyl)oxy]-(9CI);2-Oxopropyl 2-aMinobenzoate
• CAS NO: 130627-09-7
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193.2
• Product Categories: AMINOACID
• Mol File: 130627-09-7.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-Propanone,1-[(2-aminobenzoyl)oxy]-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanone,1-[(2-aminobenzoyl)oxy]-(9CI)(130627-09-7)
• EPA Substance Registry System: 2-Propanone,1-[(2-aminobenzoyl)oxy]-(9CI)(130627-09-7)

Safety Data

• Hazardous Substances Data: 130627-09-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Propanone,1-[(2-aminobenzoyl)oxy]-(9CI) is used as an intermediate in the production of various pharmaceuticals. Its unique molecular structure allows it to be a key component in the synthesis of drugs with specific therapeutic properties.
Used in Organic Synthesis:
2-Propanone,1-[(2-aminobenzoyl)oxy]-(9CI) is used as a reagent in organic synthesis. Its versatile chemical properties enable it to be a valuable building block in the creation of complex organic molecules for various applications.
Used in Medicinal Chemistry and Drug Development:
Due to its potential biological activity, 2-Propanone,1-[(2-aminobenzoyl)oxy]-(9CI) may have applications in medicinal chemistry and drug development. Researchers can explore its interactions with biological targets and evaluate its potential as a lead compound for the development of new therapeutic agents.

Upstream product

• 54550-26-4 2-Nitrobenzoesaeureacetonylester 
• 118-92-3 anthranilic acid 
• 78-95-5 chloroacetone 
• 552-16-9 ortho-nitrobenzoic acid 

Downstream Products

• 34497-54-6 3-hydroxy-2-methyl-quinolin-4(1H)-one 

Relevant articles and documents

Structural analogues of quinoline alkaloids: Straightforward route to [1,3]dioxolo[4,5-c]quinolines with antibacterial properties

Compounds bearing [1,3]dioxolo-quinoline scaffolds have been found in quinoline-based natural products; the only exception is the [1,3]dioxolo[4,5-c]quinoline moiety with a rare occurrence in both natural and synthetic derivatives. In this article, we report the preparation of diversely substituted and functionalized [1,3]dioxolo[4,5-c]quinolines using [1,3]dioxolo[4,5-c]quinoline-4-carbaldehyde (DQC) as the common intermediate. DQC was synthesized on a large scale from anthranilic acid and chloroacetone as the starting materials, with the rearrangement of acetonyl-anthranilate as the key step. The developed method allows for the simple preparation of [1,3]dioxolo[4,5-c]quinolines with various C2 substituents on the quinoline scaffold. Additionally, the synthetic route was successfully applied to the preparation of 3-hydroxyquinoline-4(1H)-ones. The target compounds were tested against representative Gram-positive/negative bacteria, and two derivatives exhibited submicromolar minimum inhibitory concentrations against Micrococcus luteus.

Preparation of 1,2-disubstituted-3-hydroxy-4(1H)-quinolinones and the influence of substitution on the course of cyclization

Synthesis of 1,2-disubstituted-3-hydroxy-4(1H)-quinolinones by the cyclization of N-substituted phenacyl or acetonyl anthranilates is described. Two methods were employed for cyclization of anthranilates. Heating in polyphosphoric acid has a wide scope of applicability. The thermal cyclization in boiling N-methylpyrrolidone is limited by steric effect.

Synthesis of 2-Substituted 1H-Benzoxazepin-5-ones

An approach to the hitherto unknown class of 1H-benz>e>oxazepin-5-ones is given based on reduction and cyclization of appropriate acyclic ortho-nitro compounds as starting material.Thus, some 2-substituted derivatives (3a-i) were synthesized by catal