130723-54-5

Basic information

• Product Name: 3-IODOPHENYLACETONITRILE
• Synonyms: 3-IODOPHENYLACETONITRILE;3-IODOBENZYL CYANIDE;3-Iodobenzyl Cyanide 130723-54-5;2-(3-Iodophenyl)acetonitrile;m-Iodobenzyl cyanide;3-Iodophenylacetonitrile 90%
• CAS NO: 130723-54-5
• Molecular Formula: C₈H₆IN
• Molecular Weight: 243.04
• EINECS: -0
• Product Categories: C8 to C9;Cyanides/Nitriles;Nitrogen Compounds;Building Blocks;C8 to C9;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 130723-54-5.mol

Chemical Properties

• Melting Point: 34-38 °C(lit.)
• Boiling Point: 138°C 12mm
• Flash Point: 138°C/12mm
• Appearance: /
• Density: 1.764g/cm³
• Vapor Pressure: 0.000674mmHg at 25°C
• Refractive Index: 1.624
• Storage Temp.: 2-8°C(protect from light)
• Solubility: soluble in Methanol
• Water Solubility: Insoluble in water
• Sensitive: Light Sensitive
• BRN: 7350695
• CAS DataBase Reference: 3-IODOPHENYLACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-IODOPHENYLACETONITRILE(130723-54-5)
• EPA Substance Registry System: 3-IODOPHENYLACETONITRILE(130723-54-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 20/21/22-36/37/38-21/22
• Safety Statements: 36/37
• RIDADR: 3439
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 130723-54-5(Hazardous Substances Data)

Usage

Uses

Used in Agrochemical Industry:
3-IODOPHENYLACETONITRILE is used as an intermediate compound for the synthesis of various agrochemicals, such as pesticides and herbicides. Its presence in these products aids in enhancing their effectiveness in controlling pests and weeds, ultimately contributing to increased crop yields and improved agricultural productivity.
Used in Pharmaceutical Industry:
3-IODOPHENYLACETONITRILE is employed as a key intermediate in the development of pharmaceutical drugs. Its unique chemical structure allows it to be used in the synthesis of various therapeutic agents, including those targeting cancer, inflammation, and other medical conditions. The compound's versatility makes it a valuable asset in the ongoing search for novel and effective medications.
Used in Dyestuff Industry:
3-IODOPHENYLACETONITRILE is utilized as a crucial component in the production of dyes and pigments. Its chemical properties enable it to impart vibrant colors and enhanced stability to the final products, making it an essential ingredient in the creation of a wide range of dyes used in various applications, such as textiles, plastics, and printing inks.

InChI:InChI=1/C8H6IN/c9-8-3-1-2-7(6-8)4-5-10/h1-3,6H,4H2

Upstream product

• 130723-53-4 3-(2-Cyanoprop-2-yl)phenyl iodide 
• 49617-83-6 m-Iodobenzyl bromide 
• 151-50-8 potassium cyanide 
• 31938-07-5 (3-bromophenyl)acetonitrile 

Downstream Products

• 30118-03-7 2-(3-Iodo-phenyl)-3-oxo-butyronitrile 
• 189278-01-1 (1S,3R,5R)-3-(3-Iodo-phenyl)-8-oxa-bicyclo[3.2.1]octane-3-carbonitrile 
• 189139-52-4 (1R,3S,5S)-3-(3-Iodo-phenyl)-8-oxa-bicyclo[3.2.1]octane-3-carbonitrile 
• 179421-14-8 4-cyano-4-(3-iodophenyl)-3,4,5,6-tetrahydro-2H-pyran 
• 21906-35-4 1-(3-Iodphenyl)-2-propanon 
• 1370557-55-3 (3-trimethylstannyl-phenyl)-acetonitrile 
• 1878-69-9 3-iodophenylacetic acid 
• 352313-60-1 C₁₈H₁₄FNO₂ 
• 352312-85-7 C₁₈H₁₅NO₂ 
• 124276-77-3 C₁₀H₈IN 
• 891657-58-2 2-(3-iodophenyl)propanenitrile 
• 130723-53-4 3-(2-Cyanoprop-2-yl)phenyl iodide 
• 1092977-40-6 (3-butylthiophenyl)-acetonitrile 
• 1189778-95-7 3-(3-iodo-phenyl)-5-(5-chloro-thiophen-2-yl-[1,3]dioxolan-2-yl)-benzo[c]isoxazole 

Relevant articles and documents

Rapid and efficient copper-catalyzed finkelstein reaction of (hetero)aromatics under continuous-flow conditions

A general, rapid, and efficient method for the copper-catalyzed Finkelstein reaction of (hetero)aromatics has been developed using continuous flow to generate a variety of aryl iodides. The described method can tolerate a broad spectrum of functional groups, including N-H and O-H groups. Additionally, in lieu of isolation, the aryl iodide solutions were used in two distinct multistep continuous-flow processes (amidation and Mg-I exchange/nucleophilic addition) to demonstrate the flexibility of this method.

Lead-discovery of bis-aromatic alkynes: A novel class of herbicides

The search for new active molecules with novel modes of action and desirable physical properties is an ongoing endeavour.[1,2] This publication describes the follow-up chemistry of a biological hit discovered in the screening system of Novartis

Organic compounds

Compounds of general formula (I) wherein the substituents are as defined in claim 1 are suitable for use as herbicides.

HETEROCYCLIC DERIVATIVES

The invention concerns a heterocyclic derivative of the formula I, or a pharmaceutically-acceptable salt there of. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.