131194-14-4Relevant articles and documents
Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof
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, (2008/06/13)
The disclosure concerns pyrimidine derivatives represented by the following general formulas [I] and [I'] and having antiviral activity, particularly antiretroviral activity such as anti-HIV activity: STR1 and pharmaceutical compositions having antiviral
A new class of HIV-1-specific 6-substituted acyclouridine derivatives: Synthesis and anti-HIV-1 activity of 5- or 6-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)
Tanaka,Baba,Hayakawa,Sakamaki,Miyasaka,Ubasawa,Takashima,Sekiya,Nitta,Shigeta,Walker,Balzarini,De Clercq
, p. 349 - 357 (2007/10/02)
A series of novel acyclouridine derivatives substituted at both the C-5 and C-6 positions were synthesized for the purpose of improving the activity of a recently reported HIV-1-specific lead, 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT). Prep
