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Z-PHE-MET-OH is a synthetic peptide composed of phenylalanine, methionine, and a hydroxyl group. It is a chemical compound widely used in biochemical and pharmaceutical research for studying enzymatic activities and as a substrate in kinematic assays.
Used in Biochemical Research:
Z-PHE-MET-OH is used as a substrate in kinematic assays for measuring the rate of enzymatic hydrolysis by proteolytic enzymes. Its role in understanding enzymatic processes in cells and tissues makes it an important chemical in biochemical research.
Used in Pharmaceutical Research:
Z-PHE-MET-OH is utilized in the development and testing of new drug candidates for treating various diseases and disorders. Its application in pharmaceutical research aids in the discovery and optimization of potential therapeutic agents.

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  • 13126-07-3 Structure
  • Basic information

    1. Product Name: Z-PHE-MET-OH
    2. Synonyms: carbobenzoxyphenylalanylmethionine;N-CARBOBENZOXY-L-PHENYLALANYL-L-METHIONINE;Z-L-PHENYLALANYL-L-METHIONINE;Z-PHE-MET-OH;N-cbz-phe-met;N-carbobenzyloxy-Phe-Met;2-[[2-(benzyloxycarbonylamino)-3-phenyl-propanoyl]amino]-4-(methylthio)butyric acid;4-methylsulfanyl-2-[[3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]butanoic acid
    3. CAS NO:13126-07-3
    4. Molecular Formula: C22H26N2O5S
    5. Molecular Weight: 430.52
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 13126-07-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 727°C at 760 mmHg
    3. Flash Point: 393.5°C
    4. Appearance: /
    5. Density: 1.256g/cm3
    6. Vapor Pressure: 3.47E-22mmHg at 25°C
    7. Refractive Index: 1.591
    8. Storage Temp.: -15°C
    9. Solubility: N/A
    10. CAS DataBase Reference: Z-PHE-MET-OH(CAS DataBase Reference)
    11. NIST Chemistry Reference: Z-PHE-MET-OH(13126-07-3)
    12. EPA Substance Registry System: Z-PHE-MET-OH(13126-07-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 13126-07-3(Hazardous Substances Data)

13126-07-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 13126-07-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,2 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13126-07:
(7*1)+(6*3)+(5*1)+(4*2)+(3*6)+(2*0)+(1*7)=63
63 % 10 = 3
So 13126-07-3 is a valid CAS Registry Number.
InChI:InChI=1/C22H26N2O5S/c1-30-13-12-18(21(26)27)23-20(25)19(14-16-8-4-2-5-9-16)24-22(28)29-15-17-10-6-3-7-11-17/h2-11,18-19H,12-15H2,1H3,(H,23,25)(H,24,28)(H,26,27)

13126-07-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-methylsulfanyl-2-[[3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]butanoic acid

1.2 Other means of identification

Product number -
Other names Cbz-L-Phe-L-Met-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13126-07-3 SDS

13126-07-3Relevant articles and documents

Convenient green preparation of dipeptides using unprotected α-amino acids

Ezawa, Tetsuya,Jung, Seunghee,Kawashima, Yuya,Noguchi, Takuya,Imai, Nobuyuki

, p. 75 - 83 (2017/01/10)

Dipeptides and amides were obtained in high yields from N-carbobenzyloxy α-amino acids and 3-phenylpropanoic acid with unprotected α-amino acids via the corresponding mixed carbonic carboxylic anhydrides using ethyl chloroformate and triethylamine by an ecological and convenient method in which the protection of C-terminals is not needed.

Convenient synthesis of C-terminal di- and tri-peptide amides from N-protected dipeptidoylbenzotriazoles

Celik, Ilhami,Abdel-Fattah, Ashraf A.A.

experimental part, p. 4923 - 4929 (2009/10/09)

N-Protected dipeptidoylbenzotriazoles react with aqueous ammonia to give dipeptide primary amides (77-98%) and with N-unprotected α-amino amides to afford tripeptide primary amides (82-86%).

Design and Synthesis of Enkephalin Analogues: Part I - Synthesis of Met-Enkephalin Alkylamides with Enhanced Analgesic Potency

Dhotre, B. J.,Chaturvedi, S.,Mathur, K. B.

, p. 828 - 833 (2007/10/02)

Synthesis of a series of alkylamides of Met-enkephalin has been achieved employing the key intermediate Boc-Tyr-Gly-Gly-Phe-Met-ONBzl (IV), obtained from Met-ONBzl by treatment with appropiate Nα-Boc-amino acid-2,4,5-trichlorophenyl esters in a

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