13134-03-7Relevant articles and documents
Ammonium acetate-basic alumina catalyzed knoevenagel condensation under microwave irradiation under solvent-free condition
Balalaie, Saeed,Nemati, Navid
, p. 869 - 875 (2000)
Ammonium acetate and basic alumina catalyzed efficiently the Knoevenagel condensation of aldehydes and ketones with active methylene compounds under solvent-free condition where olefinic products were obtained in high yields.
Molybdenum carbide as an efficient and durable catalyst for aqueous Knoevenagel condensation
Tavakolian, Mina,Najafpour, Mohammad Mahdi
, p. 16437 - 16440 (2019)
By following green chemistry principles, various molybdenum compounds as cost-effective, commercially available, heterogeneous, and benign catalysts were used for the Knoevenagel condensation reaction. Among the compounds (Mo2C, MoS2, MoB, MoSi2), molybdenum carbide showed efficient performance for the Knoevenagel condensation in aqueous media at room temperature, affording the corresponding products in high yields within a short reaction time. Notably, using this commercially available heterogeneous catalyst, the deacetalization-Knoevenagel condensation of benzaldehyde dimethyl acetal and malononitrile at room temperature could successfully proceed in excellent yield. Molybdenum carbide could be recovered five times without loss of activity with an operationally simple procedure.
Dihydro-2: H -thiopyran-3(4 H)-one-1,1-dioxide-a versatile building block for the synthesis of new thiopyran-based heterocyclic systems
Palchykov, Vitalii A.,Chabanenko, Roman M.,Konshin, Valeriy V.,Dotsenko, Victor V.,Krivokolysko, Sergey G.,Chigorina, Elena A.,Horak, Yuriy I.,Lytvyn, Roman Z.,Vakhula, Andriy A.,Obushak, Mykola D.,Mazepa, Alexander V.
, p. 1403 - 1412 (2018)
Three series of new cyclic sulfones have been prepared by a one-pot multi-component reaction (MCR) starting from the readily available dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide. The in silico screening of the synthesized compounds revealed their high anti-inflammatory, antiarthritic, antiasthmatic and antiallergic potential coupled with the strong probability levels of cystinyl aminopeptidase inhibition. The key structures were confirmed by 2D NMR techniques.
KNOEVENAGEL CONDENSATION CATALYSED BY ALUMINIUM OXIDE.
Texier-Boullet, Francoise,Foucaud, Andre
, p. 4927 - 4928 (1982)
The Knoevenagel condensation of carbonyl compounds with active methylene compounds was readily carried out with aluminium oxide as catalyst.
Porous Organic Polymers Constructed from Tr?ger's Base as Efficient Carbon Dioxide Adsorbents and Heterogeneous Catalysts
Dai, Zhifeng,Tang, Yongquan,Sun, Qi,Liu, Xiaolong,Meng, Xiangju,Deng, Feng,Xiao, Feng-Shou
, p. 1900 - 1904 (2018)
Through a radical solvothermal polymerization method, we synthesized two porous organic polymers based on Tr?ger's base (POP-TB and POP-Me-TB) from the corresponding vinyl-functionalized monomers (2,8-divinyl-6H,12H-5,11-methanodibenzo[b,f]diazocine and 2
Hydrotalcite catalysis in ionic liquid medium: A recyclable reaction system for heterogeneous Knoevenagel and nitroaldol condensation
Khan, Faiz Ahmed,Dash, Jyotirmayee,Satapathy, Rashmirekha,Upadhyay, Sarasij K.
, p. 3055 - 3058 (2004)
Knoevenagel condensation proceeds efficiently in recyclable [bmim]PF 6 and [bmim]BF4 without any catalyst, and hydrotalcites in ionic liquid serve as a safe and recyclable reaction system for both Knoevenagel as well as nitroaldol condensations.
Kinetically Controllable Pd-Catalyzed Decarboxylation Enabled [5 + 2] and [3 + 2] Cycloaddition toward Carbocycles Featuring Quaternary Carbons
Yan, Biwei,Zuo, Linhong,Chang, Xiaowei,Liu, Teng,Cui, Manying,Liu, Yang,Sun, Haiyu,Chen, Weipeng,Guo, Wusheng
supporting information, p. 351 - 357 (2021/01/26)
A decarboxylative protocol has been developed toward a range of carbocycles. The key success is based on the use of a batch of newly designed cyclic carbonates as substrates that can provide carbon-carbon zwitterion intermediate under palladium catalysis.
A new porous organic polymer containing Tr?ger's base units: Evaluation of the catalytic activity in Knoevenagel condensation reaction
Coll, Deysma,Escalona, Néstor,Jessop, Ignacio A.,Martin-Trasanco, Rudy,Niebla, Vladimir,Ortiz, Pablo A.,Pérez, Edwin,Rodríguez-González, Fidel E.,Tagle, Luis H.,Terraza, Claudio A.,Tundidor-Camba, Alain,Velázquez-Tundidor, M. V.
, (2021/08/10)
The classic Tr?ger's base polymerization of a diamine and dimethoxymethane with trifluoroacetic acid as catalyst generated a Tr?ger's base-type polymer (TBP), which exhibited the absolute insolubility in a variety of organic solvents because of its highly aggregated model. A new porous organic polymer was obtained by a simple Tr?ger's base polymerization reaction between a diamine and formaldehyde in the form of acetal in the presence of trifluoroacetic acid as catalyst. Tr?ger's base-type polymer (TBP) resulted insoluble in a wide range of organic solvents due to its rigid and aromatic structure. TBP was characterized spectroscopically (FT-IR), thermally and morphologically. As result, a thermostable and amorphous polymer bearing pores ranging between 50 and 300 nm and macro-voids of up to 12 μm was obtained. Due to the insolubility of the TBP, it was tested as a metal-free heterogeneous catalyst in the Knoevenagel condensation reaction, showing a high efficiency. For this, the optimal catalyst load, reaction time and reuse of the catalyst were studied using benzaldehyde and malononitrile as substrates. Furthermore, aldehydes with variable chain sizes and ethyl cyanoacetate replacing malononitrile were tested as substrate with a high percent of conversion (97–99%).
Controllable one-pot synthesis for scaffold diversity: Via visible-light photoredox-catalyzed Giese reaction and further transformation
Nam, Su Been,Khatun, Nilufa,Kang, Young Woo,Park, Boyoung Y.,Woo, Sang Kook
supporting information, p. 2873 - 2876 (2020/03/19)
This study presents a controllable one-pot synthesis for constructing valuable scaffolds (alcohols, 2,3-dihydrofurans, α-cyano-γ-butyrolactones, and γ-butyrolactones) via a visible-light photoredox-catalyzed Giese reaction and further transformation. This
Visible-Light Photoredox-Catalyzed α-Regioselective Conjugate Addition of Allyl Groups to Activated Alkenes
Gontala, Arjun,Woo, Sang Kook
supporting information, p. 3223 - 3228 (2020/07/06)
The α-regioselective conjugate addition of allyl groups to activated alkenes is a poorly explored area of research. Herein, we report an α-adduct and (E)-isomer selective conjugate addition of allylsilanes to activated alkenes by visible-light photoredox catalysis. The reaction involves allylic radicals that can be generated from allylsilanes through a photoinduced single-electron transfer mechanism. (Figure presented.).
