101342-40-9

Basic information

• Product Name: 4H-Pyran-3-carboxylic acid, 6-amino-5-cyano-4-(1-methylethyl)-2-phenyl-, ethyl ester
• CAS NO: 101342-40-9
• Molecular Formula: C18H20N2O3
• Molecular Weight: 312.368
• Mol File: 101342-40-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4H-Pyran-3-carboxylic acid, 6-amino-5-cyano-4-(1-methylethyl)-2-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Pyran-3-carboxylic acid, 6-amino-5-cyano-4-(1-methylethyl)-2-phenyl-, ethyl ester(101342-40-9)
• EPA Substance Registry System: 4H-Pyran-3-carboxylic acid, 6-amino-5-cyano-4-(1-methylethyl)-2-phenyl-, ethyl ester(101342-40-9)

Safety Data

• Hazardous Substances Data: 101342-40-9(Hazardous Substances Data)

Upstream product

• 13134-03-7 isobutylidene-malononitrile 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 78-84-2 isobutyraldehyde 
• 109-77-3 malononitrile 

Downstream Products

• 2216-94-6 phenylpropynoic acid ethyl ester 
• 117226-90-1 2-cyano-4-(ethoxycarbonyl)-5-hydroxy-3-isopropyl-5-phenyl-4-pentenamide 
• 117227-00-6 3-cyano-5-(ethoxycarbonyl)-4-isopropyl-6-phenyl-2H-pyran-2-one 

Relevant articles and documents

Isobutyraldehyde in the synthesis of isopropyl-substituted 4H-pyrans, 1,4-dihydropyrano[2,3-c]pyrazole, 1,4-dihydropyridines, and cyclobutane

Condensation of isobutyraldehyde with CH acids, such as acetoacetanilide, dimedone, acetoacetamide, ethyl benzoylacetate, resorcinol, cyanoacetic acid, malononitrile, 3-methyl-1-ethyl-2-pyrazolin-5-one, benzoylacetone, and cyanoacetamide, in the presence of amines gave isopropyl-substituted 4H-pyrans, 1,4-dihydropyrano[2,3-c]pyrazole, 4H-benzo[b]pyranes, 1,4-dihydropyridines, and 1,1-dicyano-2-(1-cyano-1-ethoxycarbonyl)methyl-4-isopropyl-3, 3-dimethylcyclobutane. The structure of the latter product was studied by X-ray diffraction analysis.