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ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE is a chemical compound characterized by the molecular formula C7H6F3NO2S. It is a thiazole derivative that features a trifluoromethyl group and an ethyl ester functional group. ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE is widely recognized for its role in organic synthesis and pharmaceutical research, where it serves as a versatile building block for the development of pharmaceuticals and agrochemicals. Its demonstrated biological activities, such as anti-inflammatory and analgesic properties, have positioned it as a promising candidate for drug development.

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  • 131748-96-4 Structure
  • Basic information

    1. Product Name: ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE
    2. Synonyms: ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE;Ethyl 2-(trifluoromethyl)thiazole-5-carboxylate ,97%;2-Trifluoromethylthiazole-5-carboxylic acid ethyl ester;2-(Trifluoromethyl)-5-thiazolecarboxylic acid ethyl ester;2-trifluoroMethylthiozole-5-carboxylic acid ethyl;ethyl 2-(trifluoroMethyl)-1,3-thiazole-5-carboxylate;ethyl 2-(trifluoroMethyl)thiazol-5-carboxylate
    3. CAS NO:131748-96-4
    4. Molecular Formula: C7H6F3NO2S
    5. Molecular Weight: 225.1882496
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 131748-96-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 195℃
    3. Flash Point: 72℃
    4. Appearance: /
    5. Density: 1.407
    6. Vapor Pressure: 0.433mmHg at 25°C
    7. Refractive Index: n20/D1.441
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. PKA: -2.02±0.10(Predicted)
    11. CAS DataBase Reference: ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE(CAS DataBase Reference)
    12. NIST Chemistry Reference: ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE(131748-96-4)
    13. EPA Substance Registry System: ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE(131748-96-4)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 22-36/37/38-43
    3. Safety Statements: 26-36/37
    4. RIDADR: NA 1993 / PGIII
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 131748-96-4(Hazardous Substances Data)

131748-96-4 Usage

Uses

Used in Pharmaceutical Research:
ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE is used as a building block for the production of various pharmaceuticals due to its potential biological activities, including anti-inflammatory and analgesic properties. Its unique structure allows for the creation of complex molecules with therapeutic applications.
Used in Agrochemical Development:
In the agrochemical industry, ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE is utilized as a key intermediate in the synthesis of compounds with pesticidal properties, contributing to the development of effective crop protection agents.
Used as a Reagent in Organic Synthesis:
ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE is employed as a reagent in chemical reactions to generate more complex molecules for a variety of applications, including the synthesis of advanced materials and specialty chemicals.
Used in Chemical Reactions as an Intermediate:
As an intermediate in chemical reactions, ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE facilitates the production of a range of molecules with diverse applications across different industries, highlighting its importance in the realm of chemical synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 131748-96-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,7,4 and 8 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 131748-96:
(8*1)+(7*3)+(6*1)+(5*7)+(4*4)+(3*8)+(2*9)+(1*6)=134
134 % 10 = 4
So 131748-96-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F3NO2S/c1-2-13-5(12)4-3-11-6(14-4)7(8,9)10/h3H,2H2,1H3

131748-96-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-(trifluoromethyl)-1,3-thiazole-5-carboxylate

1.2 Other means of identification

Product number -
Other names Ethyl 2-(trifluoromethyl)thiazole-5-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:131748-96-4 SDS

131748-96-4Relevant articles and documents

Guanidine derivatives, their production and insecticides

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, (2008/06/13)

An insecticidal composition containing a guanidine derivative of the formula: STR1 wherein R1 is an optionally substituted homocyclic or heterocyclic group, n is 0 or 1, R2 is a hydrogen atom or an optionally substituted hydrocarbon group, R3 is a primary, secondary or tertiary amino group, X is an electron attractive group such as nitro or trifluoroacetyl group, provided that when n is 0, R1 is an optionally substituted heterocyclic group or a salt thereof.

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