132603-48-6

Basic information

• Product Name: 3-METHYL-4-((4-NITROPHENYL)METHYLENE)-1-PHENYL-2-PYRAZOLIN-5-ONE
• Synonyms: 3-METHYL-4-((4-NITROPHENYL)METHYLENE)-1-PHENYL-2-PYRAZOLIN-5-ONE;(4E)-3-methyl-4-[(4-nitrophenyl)methylidene]-1-phenyl-4,5-dihydro-1H-pyrazol-5-one
• CAS NO: 132603-48-6
• Molecular Formula: C₁₇H₁₃N₃O₃
• Molecular Weight: 307.3
• Mol File: 132603-48-6.mol

Chemical Properties

• Boiling Point: 452.5±55.0 °C(Predicted)
• Appearance: /
• Density: 1.29±0.1 g/cm3(Predicted)
• PKA: -0.33±0.40(Predicted)
• CAS DataBase Reference: 3-METHYL-4-((4-NITROPHENYL)METHYLENE)-1-PHENYL-2-PYRAZOLIN-5-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-4-((4-NITROPHENYL)METHYLENE)-1-PHENYL-2-PYRAZOLIN-5-ONE(132603-48-6)
• EPA Substance Registry System: 3-METHYL-4-((4-NITROPHENYL)METHYLENE)-1-PHENYL-2-PYRAZOLIN-5-ONE(132603-48-6)

Safety Data

• Hazardous Substances Data: 132603-48-6(Hazardous Substances Data)

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 89-25-8 edaravone 
• 184534-61-0 1-(5-hydroxy-3-methyl-1-phenyl-4-pyrazyl)-1-(3'-indolyl)-1-(4''-nitrophenyl)methane 

Downstream Products

• 125732-52-7 C₃₃H₃₀N₈O₄ 
• 125732-48-1 5-Methyl-4-[(2-morpholin-4-yl-cyclohex-1-enyl)-(4-nitro-phenyl)-methyl]-2-phenyl-2,4-dihydro-pyrazol-3-one 
• 125732-44-7 5-Methyl-4-[(4-nitro-phenyl)-(2-piperidin-1-yl-cyclohex-1-enyl)-methyl]-2-phenyl-2,4-dihydro-pyrazol-3-one 
• 135763-58-5 5-Methyl-4-[(4-nitro-phenyl)-(2-oxo-cyclohexyl)-methyl]-2-phenyl-2,4-dihydro-pyrazol-3-one 
• 22868-34-4 2-(4-nitrophenyl)benzothiazole 
• 89-25-8 edaravone 
• 184534-61-0 1-(5-hydroxy-3-methyl-1-phenyl-4-pyrazyl)-1-(3'-indolyl)-1-(4''-nitrophenyl)methane 
• 162468-34-0 4-[Mercapto-(4-nitro-phenyl)-methyl]-5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-one 

Relevant articles and documents

Synthesis, characterization and biological applications of substituted pyrazolone core based platinum(II) organometallic compounds

New series of organometallic platinum(II) compounds (I-VI) containing the 2-phenyl-5-methyl pyrazole-3-one derivatives ligands (L1-L6) were synthesized and characterized by spectroscopic and physicochemical techniques. The synthesize

Microwave assisted one pot synthesis of 8-methyl-3,6,9-triphenyl-5,6- dihydro-9H-pyrazolo[3,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine

A facile one step synthesis of novel 8-methyl-3,6,9-triphenyl-5,6-dihydro- 9H-pyrazolo[3,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazepines 3a-1 by the reaction of (4E)-4-benzylidene-5-methyl-2-phenyl-3,4-dihydropyrazol-3,2H-ones 1a-f and 4-amino-5-phenyl-4H

The solid-state Michael addition of indole to 4-arylidene-3-methyl-5- pyrazolone

The Michael addition reactions of indole to 4-arylidene-3-methyl-1- phenyl-5-pyrazolone 1 were investigated in the solid state, by which a series of new compounds, 1-aryl-1-(3-indolyl)-1-(3'-methyl-1'-phenyl-5'-pyrazolon- 4'-yl)methanes 2, were easily obtained. This provides a feasible method of preparing novel compounds containing two heterocyclic groups at the same carbon.

Clay Catalysis: Dry Condensation of 3-Methyl-1-phenyl-5-pyrazolone with Aldehydes under Microwave Irradiation

3-Methyl-1-phenyl-5-pyrazolone (1) and arylcarboxyaldehydes (2) were condensated to 1-phenyl-3-methyl-4-(arylmethylene)-5-pyrazolone (3) in presence of acidic clay KSF without solvent under microwave irradiation.