132605-18-6Relevant articles and documents
Structure-activity relationship study of novel tissue transglutaminase inhibitors
Duval, Eric,Case, April,Stein, Ross L.,Cuny, Gregory D.
, p. 1885 - 1889 (2007/10/03)
Thieno[2,3-d]pyrimidin-4-one acylhydrazide derivatives were discovered as moderately potent inhibitors of TGase 2 (tissue transglutaminase) utilizing a fluorescence-based assay that measured TGase 2 catalyzed incorporation of the dansylated Lys derivative
Synthesis and pharmacological activities of some 3-substituted thienopyrimidin-4-one-2-thiones
Cannito, A.,Perrissin, M.,Luu-Duc, C.,Huguet, F.,Gaultier, C.,Narcisse, G.
, p. 635 - 639 (2007/10/02)
The condensation of substituted 2-amino-3-carbethoxy-thiophenes with methyl, ethyl and phenyl isothiocyanate yields the corresponding thienylthioureas which cyclize in ethanol saturated with dry hydrochloric acid to form 3-substituted thienopyrimid