1332832-15-1

Basic information

• Product Name: (S)-1-(2-Methoxyphenyl)ethanamine hydrochloride
• Synonyms: (1S)-1-(2-methoxyphenyl)ethanamine,hydrochloride;(S)-1-(2-METHOXYPHENYL)ETHANAMINE HYDROCHLRIDE
• CAS NO: 1332832-15-1
• Molecular Formula: C₉H₁₃NO*ClH
• Molecular Weight: 187.66656
• Mol File: 1332832-15-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (S)-1-(2-Methoxyphenyl)ethanamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(2-Methoxyphenyl)ethanamine hydrochloride(1332832-15-1)
• EPA Substance Registry System: (S)-1-(2-Methoxyphenyl)ethanamine hydrochloride(1332832-15-1)

Safety Data

• Hazardous Substances Data: 1332832-15-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-1-(2-Methoxyphenyl)ethanamine hydrochloride is used as an active pharmaceutical ingredient for the development of new medications targeting conditions like depression and ADHD. Its central nervous system stimulant properties make it a promising candidate for these applications.
Used in Research Applications:
In the research field, (S)-1-(2-Methoxyphenyl)ethanamine hydrochloride is utilized for studying the effects of central nervous system stimulants on various physiological and neurological processes. Its chiral nature and structural similarity to amphetamine provide valuable insights into the development of novel therapeutic agents.
Due to its psychoactive properties, the use of (S)-1-(2-Methoxyphenyl)ethanamine hydrochloride is strictly regulated to ensure its safety and efficacy in the intended applications.

Upstream product

• 1164111-48-1 C₉H₁₁NO*ClH 
• 40023-74-3 (S)-1-(2-methoxyphenyl)ethanamine 
• 17087-50-2 (+/-)-2-methoxy-α-methylbenzylamine hydrochloride 

Downstream Products

• 40023-74-3 (S)-1-(2-methoxyphenyl)ethanamine 
• 1332828-02-0 (S)-[1-(2-methoxy-phenyl)-ethyl]pyridin-2-ylmethylamine 
• 1332827-97-0 (S)-2,2,2-trifluoro-N-(1-(2-methoxyphenyl)ethyl)acetamide 

Relevant articles and documents

Rhodium-catalyzed asymmetric hydrogenation of unprotected NH imines assisted by a thiourea

Asymmetric hydrogenation of unprotected NH imines catalyzed by rhodium/bis(phosphine)-thiourea provided chiral amines with up to 97% yield and 95% ee. 1HNMR studies, coupled with control experiments, implied that catalytic chloride-bound intermediates were involved in the mechanism through a dual hydrogen-bonding interaction. Deuteration experiments proved that the hydrogenation proceeded through a pathway consistent with an imine.

Sequential reductive amination-hydrogenolysis: A one-pot synthesis of challenging chiral primary amines

Difficult-to-access chiral primary amines were formed in good to high yield and ee using a rare example of a one-pot synthesis from prochiral ketones (sequential reductive amination-hydrogenloysis). As a highlight we also demonstrate a one-pot reductive amination-hydrogenolysis-reductive amination (five reactions) of ortho-methoxyacetophenone resulting in the chiral diamine 1-(2-methoxyphenyl)ethyl-(2-pyridylmethyl)-amine (4) (58% overall yield, >99% ee), a new organocatalyst for aqueous enantioselective aldol reactions. Copyright

COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS

The present invention relates to derivatized cyclofructan compounds, compositions comprising derivatized cyclofructan compounds, and methods of using compositions comprising derivatized cyclofructan compounds for chromatographic separations of chemical species, including enantiomers. Said compositions may comprise a solid support and/or polymers comprising derivatized cyclofructan compounds.