133964-40-6

Basic information

• Product Name: Propanamide, 2-hydroxy-N-(1-methylethyl)-, (R)- (9CI)
• Synonyms: Propanamide, 2-hydroxy-N-(1-methylethyl)-, (R)- (9CI)
• CAS NO: 133964-40-6
• Molecular Formula: C6H13NO2
• Molecular Weight: 131.17292
• Product Categories: ACETYLGROUP
• Mol File: 133964-40-6.mol

Chemical Properties

• Boiling Point: 275.5±23.0 °C(Predicted)
• Appearance: /
• Density: 0.995±0.06 g/cm3(Predicted)
• PKA: 13.41±0.20(Predicted)
• CAS DataBase Reference: Propanamide, 2-hydroxy-N-(1-methylethyl)-, (R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, 2-hydroxy-N-(1-methylethyl)-, (R)- (9CI)(133964-40-6)
• EPA Substance Registry System: Propanamide, 2-hydroxy-N-(1-methylethyl)-, (R)- (9CI)(133964-40-6)

Safety Data

• Hazardous Substances Data: 133964-40-6(Hazardous Substances Data)

Upstream product

• 79-33-4 L-Lactic acid 
• 75-31-0 isopropylamine 
• 687-47-8 (S)-Ethyl lactate 
• 97-64-3 ethyl 2-hydroxypropionate 
• 547-64-8 methyl lactate 

Downstream Products

• 54523-48-7 N-isopropyl pyruvamide 

Relevant articles and documents

FORUMLATIONS

This invention relates to the use of lactamide compounds of formula (I): CH3CH(OH)C(=O)NR1R2, where R1 and R2 are each independently hydrogen; or C1-6 alkyl, C2-6 alkenyl or C3-6 cycloalkyl, each of which is optionally substituted by up to three substituents independently selected from phenyl, hydroxy, C1-5 alkoxy, morpholinyl and NR3R4 where R3 and R4 are each independently C1-3 alkyl; or phenyl optionally substituted by up to three substituents independently selected from C1-3 alkyl; or R1 and R2 together with the nitrogen atom to which they are attached form a morpholinyl, pyrrolidinyl, piperidinyl or azepanyl ring, each of which is optionally substituted by up to three substituents independently selected from C1-3 alkyl, in formulations to reduce the toxicity associated with other formulation components; to the use of certain lactamide compounds as solvents, especially in formulations, particularly in agrochemical formulations and in environmentally friendly formulations; to novel lactamide compounds; and to processes for preparing lactamide compounds.

Enantioselective hydrogenation of α-ketoamides over Pt/A12O3 modified by cinchona alkaloids

Pyruvamide and its N-alkylated derivatives have been synthesised and hydrogenated enantioselectively to the corresponding alcohols over an alumina-supported Pt catalyst chirally modified by adsorbed cinchonidine. Depending on the substrate structure and r

Inexpensive Reagents for the Synthesis of Amides from Esters and for Regioselective Opening of Epoxides

Lithium aluminum amides , 6a-6d, easily prepared in Et2O or THF from 1 equiv of LiAlH4 and 5 equiv of amine, proved to be efficient reagents for the synthesis of secondary amides from esters (ca. 100 percent with unhindered amines and 92 percent with t-BuNH2).They also open aryl epoxides with very high regioselectivity to give 97-98 percent of the β-amino-α-arylethanols (corresponding to the SN2 mechanism).