97-64-3Relevant articles and documents
Ni-Catalyzed C(sp3)–O Arylation of α-Hydroxy Esters
Monteith, John J.,Rousseaux, Sophie A. L.
supporting information, p. 9485 - 9489 (2021/12/09)
A Negishi cross-coupling of α-hydroxy ester derivatives and arylzinc reagents has been developed. This reaction tolerates both primary and secondary C(sp3)–O alcohol precursors and achieves efficient cross-coupling under Ni catalysis without the need for added external metal reductant, photocatalyst, or additives. The arylation of readily accessible C(sp3)–O electrophiles in this operationally simple, rapid, and mild reaction provides a complementary way of accessing desirable α-aryl ester products.
One-pot conversion of dihydroxyacetone into ethyl lactate by Zr-based catalysts
Shi, Junjun,Li, Fukun,Zhang, Jie,Li, Ning,Wang, Xingmin,Zhang, Xianming,Liu, Yunqi
, p. 10935 - 10940 (2021/03/23)
Efficient strategies for producing bio-based reagents from sustainable biomass are highly attractive for cost-effective sustainable manufacturing. In this study, a series of eco-friendly Zr-based catalysts (basic zirconium carbonate, zirconium dioxide and zirconium hydroxide) were investigated for the efficient conversion of dihydroxyacetone to ethyl lactate in a one-pot system, in which basic zirconium carbonate exhibited the best performance with 100% dihydroxyacetone conversion and 85.3% EL (ethyl lactate) yield at 140 °C, 4.0 h and 1.0 MPa N2. The improved activity of basic zirconium carbonate could be attributed to the synergistic effect among acid and base active sites. Furthermore, this low-cost catalyst shows improved thermochemical stability and recyclability under optimal conditions, where no significant decrease in activity was observed after three runs. This catalytic process could be identified as a promising alternative to produce ethyl lactate from renewable biomass and its derivatives.
Process method for producing ethyl lactate by using reactive distillation dividing wall tower technology
-
Paragraph 0039; 0040; 0046-0049, (2020/02/14)
The invention provides a process method for producing ethyl lactate by using a reactive distillation dividing wall tower technology. According to the process, the production of ethyl lactate is completed in a reactive distillation dividing wall tower, an esterification reaction of lactic acid and ethanol is completed in a middle section feeding side reaction section of the reactive distillation dividing wall tower to generate ethyl lactate and water, and the separation of ethanol and esterification product water is completed through a middle section extraction side rectification section, meanwhile, ethyl lactate purification is realized in a middle section feeding side stripping section and a middle section extracting side stripping section, and finally a food-grade ethyl lactate product is obtained at the bottom of the tower. Compared with the prior art, the process has the advantages of high ethyl lactate product yield, high equipment integration, short process flow, low one-time investment, low operation cost and the like.