134604-07-2

Basic information

• Product Name: 1-CYANO-2-BROMO-5-NITROBENZENE
• Synonyms: 2-BROMO-5-NITROBENZONITRILE;1-CYANO-2-BROMO-5-NITROBENZENE;2-Bromo-1-cyano-5-nitrobenzene;2-Bromo-5-nitrobenzonitrile 98%;2-BroMo-5-nitrobenzonitrile;Bromo-5-nitrobenzonitrile
• CAS NO: 134604-07-2
• Molecular Formula: C₇H₃BrN₂O₂
• Molecular Weight: 227.01
• Product Categories: blocks;Bromides;Carboxes;NitroCompounds;Aromatic Nitriles;C6 to C7Chemical Synthesis;Cyanides/Nitriles;New Products for Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 134604-07-2.mol

Chemical Properties

• Melting Point: 118-120 °C
• Boiling Point: 321.138 °C at 760 mmHg
• Flash Point: 148.019 °C
• Appearance: /
• Density: 1.812 g/cm³
• Vapor Pressure: 0.000304mmHg at 25°C
• Refractive Index: 1.638
• Storage Temp.: 2-8°C
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 1-CYANO-2-BROMO-5-NITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CYANO-2-BROMO-5-NITROBENZENE(134604-07-2)
• EPA Substance Registry System: 1-CYANO-2-BROMO-5-NITROBENZENE(134604-07-2)

Safety Data

• Hazard Codes: Xi
• Statements: 22-36/37/38
• Safety Statements: 26-36/37-60
• RIDADR: 2811
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 134604-07-2(Hazardous Substances Data)

Usage

Chemical Properties

Type of white crystal

InChI:InChI=1/C7H3BrN2O2/c8-7-2-1-6(10(11)12)3-5(7)4-9/h1-3H

Upstream product

• 17333-81-2 o-bromobenzenediazonium 
• 619-24-9 3-nitrobenzonitrile 
• 586-78-7 para-nitrophenyl bromide 
• 84459-32-5 2-bromo-5-nitrobenzaldehyde 
• 17420-30-3 5-nitroanthranilonitrile 
• 106-95-6 allyl bromide 
• 2042-37-7 o-cyanobromobenzene 
• 7697-37-2 nitric acid 

Downstream Products

• 1161362-06-6 2-(2-methylpyridin-4-yl)-5-nitrobenzonitrile 
• 1219024-62-0 2-[2-(diphenylmethylene)hydrazino]-5-nitrobenzonitrile 
• 78252-11-6 2-Morpholin-4-yl-5-nitro-benzonitrile 
• 146070-32-8 2-aminophenyl 2-cyano-4-nitrophenyl sulfide 

Relevant articles and documents

Method for preparing 3,5-disubstituted oxadiazole compound

The invention discloses a method for preparing a 3,5-disubstituted oxadiazole compound N-((3-(2-bromo-5-nitrophenyl)-1,2,4-oxadiazole-5-yl)methyl)ethylamine. 4-nitrobromobenzene used as a starting material undergoes hydroformylation, oximation, eliminatio

Palladium-catalyzed highly selective ortho-halogenation (I, Br, Cl) of arylnitriles via sp2 C-H bond activation using cyano as directing group

A palladium-catalyzed ortho-halogenation (I, Br, Cl) of arylnitrile is described. The optimal reaction conditions were identified after examining various factors such as catalyst, additive, solvent, and reaction temperature. Using cyano as the directing group, the halogenation reaction gave good to excellent yields. The method is compatible to the arylnitriles with either electron-withdrawing or electron-donating groups. The reaction is available to the substrate in at least gram scale. The present method was successfully applied to the synthesis of the precursors of paucifloral F and isopaucifloral F.

Aromatic allylation via diazotization: Metal-free C-C bond formation

A new method for the synthesis of allyl aromatic compounds not involving any metal-containing reagent or catalyst has been developed. Arylamines substituted with a large number of different substituents were converted via diazotizative deamination with tert-butyl nitrite in allyl bromide and acetonitrile to the corresponding allyl aromatic compounds. The allylation reaction was found to be suitable for larger scale synthesis due to short reaction times, a nonextractive workup, and robustness toward moisture, air, and type of solvent.