135925-33-6 Usage
Uses
Used in Chemical Synthesis:
Ethyl 2,5-dichloro-1,3-thiazole-4-carboxylate is used as a reactant in the preparation of halogenated thiazole isocyanates. These isocyanates are important intermediates in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. The presence of the chlorine atoms in the thiazole ring allows for further functionalization and modification of the molecule, making it a versatile building block in organic chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethyl 2,5-dichloro-1,3-thiazole-4-carboxylate is used as a key intermediate in the synthesis of drugs with potential therapeutic applications. The halogenated thiazole isocyanates derived from Ethyl 2,5-dichloro-1,3-thiazole-4-carboxylate can be further reacted with other molecules to form bioactive compounds that target specific receptors or enzymes in the body, leading to the development of new medications for various diseases.
Used in Agrochemical Industry:
Ethyl 2,5-dichloro-1,3-thiazole-4-carboxylate also finds application in the agrochemical industry, where it is used as a starting material for the synthesis of halogenated thiazole-based pesticides. These pesticides can be used to control pests and diseases in agriculture, contributing to increased crop yields and food security.
Check Digit Verification of cas no
The CAS Registry Mumber 135925-33-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,9,2 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 135925-33:
(8*1)+(7*3)+(6*5)+(5*9)+(4*2)+(3*5)+(2*3)+(1*3)=136
136 % 10 = 6
So 135925-33-6 is a valid CAS Registry Number.
135925-33-6Relevant articles and documents
Synthesis of 2,5-dihalothiazole-4-carboxylates
Okonya, John F,Al-Obeidi, Fahad
, p. 7051 - 7053 (2007/10/03)
An efficient synthesis of 2,5-dihalothiazole-4-carboxylates has been described. Halogenation of aminothiazole carboxylate with NBS or NCS and subsequent diazotization with isoamyl nitrite and halogenation with CuBr2, CuCl2 or CH2I2 provided the corresponding diahalothiazole derivatives. The four-step process described is amenable to scale-up and requires no chromatographic purification in all the steps.
Synthesis and Reactions of Halogenated Thiazole Isocyanates
South, Michael S.
, p. 1003 - 1011 (2007/10/02)
A synthesis of 2-chloro-4-(trifluoromethyl)-5-isocyanatothiazole and 2,5-dichloro-5-isocyanatothiazole is described via the "Curtius Rearrangement" performed under anhydrous conditions.The synthetic procedure described allows for the isolation, storage, a
4-substituted 5-chloro-2-hydrazinothiazoles
-
, (2008/06/13)
4-Substituted 5-chloro-2-hydrazinothiazoles of the formula STR1 in which R represents CHF2, CF3, CN or COOR1, where R1 represents C1 -C4 -alkyl. They are useful as pesticides and as intermediates for other pesticides.
