136366-42-2

Basic information

• Product Name: 3-broMo-4-ethyoxylbenzonitrile
• Synonyms: 3-broMo-4-ethyoxylbenzonitrile;3-broMo-4-ethoxybenzonitrile
• CAS NO: 136366-42-2
• Molecular Formula: C₉H₈BrNO
• Molecular Weight: 226.06992
• Mol File: 136366-42-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-broMo-4-ethyoxylbenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-broMo-4-ethyoxylbenzonitrile(136366-42-2)
• EPA Substance Registry System: 3-broMo-4-ethyoxylbenzonitrile(136366-42-2)

Safety Data

• Hazardous Substances Data: 136366-42-2(Hazardous Substances Data)

Upstream product

• 75-03-6 ethyl iodide 
• 103260-55-5 2-bromo-1-ethoxy-4-methylbenzene 
• 1428637-14-2 C₁₀H₁₂BrNO₂ 
• 2315-86-8 3-bromo-4-hydroxybenzonitrile 

Relevant articles and documents

COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.

2 - (3-cyano-4-alkoxy) phenyl-4-substituted thiazole-5- formic acid class compound, composition and its preparation and use

The invention relates to a 2-(3-cyano-4-alkoxy) phenyl-4-substituted thiazole-5-formic acid compound which has xanthine oxidase inhibitory activity and is shown in a general formula I, a composition and preparation methods thereof. The invention also relates to applications of the compound and the composition thereof to preparation of medicaments for treating and/or preventing hyperuricemia and gout diseases. In the formula I, R2 is substituted or unsubstituted phenyl or a substituted or unsubstituted heteroaromatic radical, R1 is a substitutive aliphatic group of a straight chain or a branched chain, substituted or unsubstituted alicyclic hydrocarbonyl or substituted or unsubstituted aryl alkyl and A is an oxygen atom, a sulfur atom or a nitrogen atom.

Ruthenium-catalyzed intramolecular selective halogenation of O-methylbenzohydroximoyl halides: A new route to halogenated aromatic nitriles

The intramolecular halogenation of O-methylbenzohydroximoyl halides in the presence of a Ru catalyst and the ligand diphenylacetylene afforded halo substituted aromatic nitriles in a highly regioselective manner. Further, substituted nitriles were converted into substituted tetrazole derivatives in the presence of NaN3 and I2.

NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS

The present application relates to thiazolylidene containing compounds of formula (I) wherein R1, R2, R3, R4, L2 and A are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS

The present invention relates to pyrrole and pyrazole compounds of formula (I) and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression. The compounds act as potentiators on glutamate receptors, in particular AMPA and the GluR family.