13698-16-3

Basic information

• Product Name: DCU
• Synonyms: Carbamic acid, dichloro-, ethyl ester;Ethyl dichlorocarbamate;N,N-DICHLOROURETHANE;DCU;N,N-DICHLOROURETHANE, TECH., 90%;Ethyl N,N-dichlorocarbamate;N,N-Dichlorourethane,98%;N,N-DichlorourethaneDCU
• CAS NO: 13698-16-3
• Molecular Formula: C₃H₅Cl₂NO₂
• Molecular Weight: 157.98
• Mol File: 13698-16-3.mol

Chemical Properties

• Boiling Point: 55-56 °C15 mm Hg(lit.)
• Flash Point: 206 °F
• Appearance: Clear yellow/Liquid
• Density: 1.349 g/mL at 25 °C(lit.)
• Vapor Pressure: 2.55mmHg at 25°C
• Refractive Index: n20/D 1.46(lit.)
• Storage Temp.: 0-6°C
• PKA: -4.16±0.70(Predicted)
• CAS DataBase Reference: DCU(CAS DataBase Reference)
• NIST Chemistry Reference: DCU(13698-16-3)
• EPA Substance Registry System: DCU(13698-16-3)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38-40
• Safety Statements: 26-36/37/39
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 13698-16-3(Hazardous Substances Data)

Usage

Chemical Properties

clear yellow liquid

InChI:InChI=1/C3H5Cl2NO2/c1-2-8-3(7)6(4)5/h2H2,1H3

Upstream product

• 539-71-9 diethyl ethane-1,1-diyldicarbamate 
• 16844-21-6 N-Chlorourethan 
• 541-41-3 chloroformic acid ethyl ester 
• 51-79-6 urethane 
• 7732-18-5 water 
• 7782-50-5 chlorine 
• 191276-34-3 (4S,5R)-N-(tert-butoxycarbonyl)-2-(2,4-dimethoxyphenyl)-4-iso-butyl-5-oxazolidinecarboxylic acid 

Downstream Products

• 13800-04-9 ethyl (2-chloro-2-phenylethyl)carbamate 
• 88-06-2 2,4,6-Trichlorophenol 
• 3693-53-6 N,N'-methanediyl-bis-carbamic acid diethyl ester 
• 52144-68-0 N-(β-Chlor-β-phenylethyl)-N-chlor-urethan 
• 4068-78-4 methyl 5-chloro-2-hydroxybenzoate 
• 7693-77-8 5-phenyloxazolidin-2-one 
• 18506-88-2 N-(ethoxycarbonyl)-p-nitrobenzenesulfinimidoyl chloride 
• 13698-13-0 Ethyl N-(2-chloro-1,2-diphenylethyl)carbamate 
• 5336-13-0 1-chloro-2-di(ethoxycarbonylamino)ethane 
• 54858-79-6 [1-Dimethylamino-meth-(E)-ylidene]-carbamic acid ethyl ester 
• 5336-12-9 1,1-Bis-aethoxycarbonylamino-2-chlor-butan 
• 59357-92-5 N-(2.2.2-Trichlor-ethyl)-carbaminsaeure-ethylester 
• 3693-54-7 diethyl N,N'-benzylidenebis(carbamate) 
• 4098-70-8 trans-ethyl N-2-chlorocyclohexylcarbamate 

Relevant articles and documents

New effective synthetic method for preparation of N,N-dichlorocarbamates

A rapid, efficient, economical, and easy-to-scale method for the effective conversion of carbamates to corresponding N,N-dichlorocarbamates by using sodium hypochlorite in acidic medium has been described. N,N-Dichlorocarbamates were obtained in quantitative yield through a simple workup in reduced reaction time.

Detoxification of O, S-diethyl methyl phosphonothiolate (OSDEMP), a simulant of VX, by N, N-dichlorourethane as an effective decontaminating agent

N, N-Dichlorourethane has been synthesized and characterized by FT-IR, NMR. Efficiency of this compound as decontaminant has been evaluated by the reaction of O, S-diethyl methyl phosphonothiolate (OSDEMP), a simulant of VX at RT. The decontamination reaction has been monitored by gas chromatography (GC) and the products have been identified by GC-MS.

Copper-promoted iodovinylation of amides: synthesis of β-functionalized enamides

We studied the addition of nitrogen radicals to ynol ethers in order to form β-functionalized enamides. Poor yields are reported. On the other hand, we observed that copper coupling between 1,2-diiodoethene and various amides leads to β-functionalized enamides in high yields with complete stereocontrol.

TAXANE DERIVATIVES FUNCTIONALIZED AT THE 14- POSITION AND A PROCESS FOR THE PREPARATION THEREOF

A general process for the functionalization at the 14- position of 13-ketobaccatin derivatives of formula I to give derivatives of formula II wherein the substituents are as defined in the disclosure. The conversion of compounds of formula II in compounds of formula III, wherein the substituents are as defined in the disclosure, is also described.