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CAS

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1381757-44-3

Dabigatran Etexilate N-Oxide is a metabolite of Dabigatran Etexilate, which is an oral anticoagulant and direct thrombin inhibitor. It plays a significant role in the regulation of blood clotting and is derived from the parent compound used for medical purposes.

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  • 1381757-44-3 Structure

  • Basic information

    1. Product Name: Dabigatran Etexilate N-Oxide
    2. Synonyms: Dabigatran Etexilate N-Oxide;Dabigatran Etexilate N-Oxide (iMpurity N);ODWAOSMOSLZPGX-UHFFFAOYSA-N;(Z)-2-(N-(3-ethoxy-3-oxopropyl)-2-(((4-(N'-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-1H-benzo[d]imidazole-5-carboxamido)pyridine 1-oxide
    3. CAS NO:1381757-44-3
    4. Molecular Formula: C34H41N7O6
    5. Molecular Weight: 643.73264
    6. EINECS: N/A
    7. Product Categories: Isotope Labeled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 1381757-44-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.26±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 9.88±0.46(Predicted)
    10. CAS DataBase Reference: Dabigatran Etexilate N-Oxide(CAS DataBase Reference)
    11. NIST Chemistry Reference: Dabigatran Etexilate N-Oxide(1381757-44-3)
    12. EPA Substance Registry System: Dabigatran Etexilate N-Oxide(1381757-44-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1381757-44-3(Hazardous Substances Data)

1381757-44-3 Usage

Uses

Used in Pharmaceutical Industry:
Dabigatran Etexilate N-Oxide is used as an active metabolite for the regulation of blood clotting. It serves as a crucial component in the management and prevention of blood clot-related disorders, such as stroke and deep vein thrombosis, by directly inhibiting thrombin's activity.

Check Digit Verification of cas no

The CAS Registry Mumber 1381757-44-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,8,1,7,5 and 7 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1381757-44:
(9*1)+(8*3)+(7*8)+(6*1)+(5*7)+(4*5)+(3*7)+(2*4)+(1*4)=183
183 % 10 = 3
So 1381757-44-3 is a valid CAS Registry Number.

1381757-44-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(N-(3-ethoxy-3-oxopropyl)-2-((4-(N'-(hexyloxycarbonyl)carbamimidoyl)phenylamino)methyl)-1-methyl-1H-benzo[d]imidazole-5-carboxamido)pyridine-1-oxide

1.2 Other means of identification

Product number -
Other names Dabigatran Etexilate N-Oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1381757-44-3 SDS

1381757-44-3Downstream Products

1381757-44-3Relevant articles and documents

PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND ITS SALTS

-

, (2012/06/30)

The Present Invention Provides An Improved Process For The Preparation Of 1-methyl-2-[n-[4-(n-n-hexyloxycarbonylamidino) Phenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-n-(2-pyridyl)-n-(2-ethoxycarbonylethyl)amide Compound Of Formula-1 And Its Methanesulfonate Salt Compound Of Formula-1a.

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