138320-27-1

Basic information

• Product Name: 2-(2-ForMylphenoxy)hexanoic acid
• Synonyms: 2-(2-ForMylphenoxy)hexanoic acid
• CAS NO: 138320-27-1
• Molecular Formula: C₁₃H₁₆O₄
• Molecular Weight: 236.26374
• Mol File: 138320-27-1.mol

Chemical Properties

• Boiling Point: 394.6±17.0 °C(Predicted)
• Appearance: /
• Density: 1.165±0.06 g/cm3(Predicted)
• PKA: 3.09±0.10(Predicted)
• CAS DataBase Reference: 2-(2-ForMylphenoxy)hexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-ForMylphenoxy)hexanoic acid(138320-27-1)
• EPA Substance Registry System: 2-(2-ForMylphenoxy)hexanoic acid(138320-27-1)

Safety Data

• Hazardous Substances Data: 138320-27-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(2-Formylphenoxy)hexanoic acid is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique structure allows for the creation of a diverse range of compounds with potential medicinal applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(2-Formylphenoxy)hexanoic acid is utilized as a key component in the synthesis of agrochemicals. Its incorporation into these products can enhance their effectiveness in agricultural applications, such as pest control and crop protection.
Used in Materials Science:
2-(2-Formylphenoxy)hexanoic acid is employed in the field of materials science for the development of new materials with specific properties. Its versatility allows it to be integrated into various material formulations, potentially improving their performance and expanding their range of applications.
Overall, 2-(2-Formylphenoxy)hexanoic acid is a valuable compound with a broad spectrum of applications across different industries, making it an essential component in scientific research and commercial development.

Upstream product

• 5445-19-2 methyl 2-bromohexanoate 
• 90-02-8 salicylaldehyde 
• 138320-26-0 methyl 2-(2-formylphenoxy)hexanoate 

Downstream Products

• 4265-27-4 2-n-butylbenzo[b]furan 
• 97025-19-9 2-(o-carboxyphenoxy)hexanoic acid 
• 335153-21-4 2-(2-formyl-4-nitrophenoxy)hexanoic acid 
• 19774-82-4 amiodarone hydrochloride 
• 52490-15-0 2-n-Butyl-3-(4-hydroxy-benzoyl)-benzofuran 
• 1951-26-4 2-n-butyl-3-(3',5'-diiodo-4'-hydroxybenzoyl)benzofuran 
• 83790-87-8 2-n-butyl 3-(4-methoxy benzoyl)-benzofuran 
• 95486-76-3 1-[3-(2-butylbenzofuranyl)]-2-(4-hydroxyphenyl)ethanone 
• 199725-34-3 1-[3-(2-butylbenzofuranyl)]-2-phenylethanone 
• 94968-16-8 1-<3-(2-butylbenofuranyl)>-2-(4-methoxyphenyl)ethanone 

Relevant articles and documents

Preparation method of amiodarone hydrochloride intermittent

The invention belongs to the field of medicine synthesis, and relates to a preparation method of an amiodarone hydrochloride intermittent. The method is characterized by including the following stepsthat 1, under an alkaline condition, in the presence of a phase transfer catalyst, a compound 1 and a compound 2 are subjected to nucleophilic substitution reaction to obtain a compound 3; 2, under analkaline condition, the compound 3 is hydrolyzed to generate a compound 4; 3, the compound 4 is subjected to intramolecular aldol condensation, decarboxylation and dehydration to obtain a compound 5;4, a compound 6 and thionyl chloride are subjected to heating reaction to obtain a compound 7; 5, under the presence of lewis acid, the compound 5 and the compound 7 are subjected to friede-crafts acylation reaction to obtain a compound 8; 6, under the presence of lewis acid, the compound 8 is subjected to demethylation to generate a compound 9, namely the amiodarone hydrochloride intermittent 2-butyl-3-(4-hydroxybenzoyl)benzofuran. The preparation method of the amiodarone hydrochloride intermittent has the advantages of being short in reaction time, high in product purity and high in yield,and the amiodarone hydrochloride intermittent is suitable for large-scale industrial production.

Amiodarone hydrochloride preparation method

The invention belongs to the field of medicine, and especially relates to an amiodarone hydrochloride preparation method. The method takes 2-hydroxybenzaldehyde and 2-alkyl halohexoic acid ester as the raw materials to prepare 2-butylbenzofuran, 2-butylbenzofuran is taken as the raw material, and is subjected to the steps of friedel-crafts acylation, demethylation, iodination, etherification and salt forming to obtain the amiodarone hydrochloride. By employing the method, the raw materials have the advantages of low cost and easy acquisition, the process is simple, and 2-butylbenzofuran and amiodarone hydrochloride with high purity and high yield can be obtained, the cost is low, the waste water is little, and the method is suitable for industrial production.

Intermediates for making a bezofuran or benzothiophene derivative nitrated in position 5 and uses thereof

The invention concerns novel nitroaromatic compounds of general formula (I′) wherein: R, R′1, R2, Z and n are as defined in claim 1. The invention also concerns a method for preparing nitroaromatic compounds nitrated in position 4. The invention further c

Benzofuran Systems. Synthesis and Biological Examination of 1-(3-Benzofuranyl)-2-phenylethanones

Novel 1-(3-benzofuranyl)-2-phenylethanones 4a-d have been prepared by acetylation of 2-alkylbenzofurans 2a-c with phenylacetyl chlorides 3a-b. The methoxy derivatives 4b-d have been demethylated to the corresponding phenols 5b-d with pyridinium hydrochloride. An attempt to obtain the derivatives of 4d and 5a iodinated in the phenyl ring has been undertaken. The novel compounds have been characterized by ir and nmr spectra and their biological activity examined.

Synthesis of 2-Phenoxyhexanal and 2-(o-Formylphenoxy)Hexanoic Acid and Its Derivatives

The paper describes the synthesis of 2-phenoxyhexanal and 2-(o-formylphenoxy)hexanoic acid and its derivatives which are intermediate compounds in the synthesis of new heterocyclic compounds.Key words: 2-phenoxyhexanal, 2-phenoxyhexanoic acid derivatives, 2-butylbenzofurane