- An efficient and recyclable nanoparticle-supported cobalt catalyst for quinoxaline synthesis
-
The syntheses of quinoxalines derived from 1,2-diamine and 1,2-dicarbonyl compounds under mild reaction conditions was carried out using a nanoparticle-supported cobalt catalyst. The supported nanocatalyst exhibited excellent activity and stability and it
- Rajabi, Fatemeh,Alves, Diego,Luque, Rafael
-
-
Read Online
- ZnO-beta zeolite mediated simple and efficient method for the one-pot synthesis of quinoxaline derivatives at room temperature
-
A rapid and an efficient one-pot method for the synthesis of quinoxalines catalysed by ZnO-beta zeolite at room temperature is described. This environmentally benign method provides several advantages over methods that are currently employed such as a simple work-up, mild reaction conditions, good to excellent yields, and a process to recover and reuse the catalyst for several cycles with consistent activity. Versita Warsaw and Springer-Verlag Wien 2010.
- Katkar, Santosh S.,Mohite, Pravinkumar H.,Gadekar, Lakshman S.,Arbad, Balasaheb R.,Lande, Machhindra K.
-
-
Read Online
- An efficient and green procedure for the synthesis of quinoxaline derivatives using 3,5-bis(Trifluoromethyl)phenylammonium triflate (bfpat) organocatalyst
-
The application of 3,5-bis(trifluoromethyl)phenylammonium triflate (BFPAT) as a conven-ient new organocatalyst for the synthesis of quinoxaline derivatives is described. In the presence of BFPAT, one-pot synthesis of a wide variety of quinoxaline derivati
- Alipour, Mandana,Hossaini, Zinatossadat,Khaksar, Samad,Rostami-Charati, Faramarz
-
p. 183 - 186
(2021/03/19)
-
- NaOH-Mediated Direct Synthesis of Quinoxalines from o-Nitroanilines and Alcohols via a Hydrogen-Transfer Strategy
-
A NaOH-mediated sustainable synthesis of functionalized quinoxalines is disclosed via redox condensation of o-nitroamines with diols and α-hydroxy ketones. Under optimized conditions, various o-nitroamines and alcohols are well tolerated to generate the desired products in 44-99% yields without transition metals and external redox additives.
- Wang, Yan-Bing,Shi, Linlin,Zhang, Xiaojie,Fu, Lian-Rong,Hu, Weinan,Zhang, Wenjing,Zhu, Xinju,Hao, Xin-Qi,Song, Mao-Ping
-
p. 947 - 958
(2021/01/14)
-
- Dowex 50W: Mild efficient reusable heterogeneous catalyst for synthesis of quinoxaline derivatives in aqueous medium
-
An efficient, simple and eco-friendly procedure is reported in presence of heterogeneous Dowex 50W catalyst in aqueous medium under refluxing condition to produce quinoxaline derivatives. Catalyst has participated in condensation reaction between 1,2-diamines and various aromatic 1,2-diketones smoothly with excellent yield of the products in short reaction times. Dowex 50W was used more than five times in this reaction separately and showed an excellent recyclability throughout the reaction.(figure presented).
- Datta, Arup,Halder, Samiran
-
p. 1218 - 1224
(2021/02/09)
-
- Quinoxaline derivatives and application thereof in organic light-emitting devices
-
The present invention discloses a novel organic compound having a structure represented by the formula shown in the specification, wherein L1 and L2 are each independently selected from one of a single bond, a substituted or unsubstituted C6-C30 arylene group, and a substituted or unsubstituted C3-C30 heteroarylene group, wherein Ar1 is selected from one of substituted or unsubstituted C3-C30 heteroaryl groups containing at least two heteroatoms, and Ar2 is selected from one of substituted or unsubstituted C6-C30 aryl groups and substituted or unsubstituted C3-C30 heteroaryl groups. When the compound provided by the invention is used as a luminescent material in an OLED device, excellent device performance and stability are shown. The invention also discloses an organic light-emitting device adopting the compound with the general formula.
- -
-
Paragraph 0038-0042
(2020/06/20)
-
- Synthesis method of quinoxaline heterocyclic derivative
-
The invention discloses a synthesis method of a quinoxaline heterocyclic derivative. An intermolecular redox reaction and a condensation cyclization reaction are carried out on an o-nitroaniline compound and an o-diol compound under the action of a water-soluble alkali to prepare the quinoxaline heterocyclic derivative in one step. Expensive transition metal catalysts and ligands do not need to beused, the water-soluble alkali is used as an accelerant and can be removed in a water washing manner, so that the product has no transition metal residue, the product is easy to separate, the recovery rate is high, and the method is simple in condition, easy to operate and low in equipment requirement; and the water-soluble alkali is used as the accelerant, so the unique byproduct is water, the atom economy is high, and the method has good research and industrial application prospects.
- -
-
Paragraph 0074-0077
(2020/05/30)
-
- N-Bromosuccinimide-Mediated Synthesis of Substituted Quinoxalines
-
An efficient and simple N-bromosuccinimide-mediated two-step synthesis of substituted quinoxalines from 1,2-diarylacetylenes and 1,2-diaminobenzenes in boiling AcOH, during a one-pot procedure has been developed. All the structures of the substituted quinoxalines were confirmed, some by single-crystal X-ray crystallography. Possible reaction pathways were discussed, and some data were matched with the previous work.
- Chan, Chieh-Kai,Chang, Meng-Yang
-
p. 3785 - 3793
(2016/10/30)
-
- Yb/NaY molecular sieve catalyst to catalyze the synthesis method for ensuring
-
The invention relates to a method for synthesizing a quinoxaline compound under catalysis of a Yb/NaY molecular sieve catalyst. The method specifically comprises the following steps of (a) mixing alpha-hydroxyketone, o-phenylenediamine, morpholine and the Yb/NaY molecular sieve catalyst, adding a solvent, and performing stirring and refluxing for 4 to 6 hours at 75 to 85 DEG C; (b) filtering the mixture obtained in the step (a), recycling a filter residue which is the Yb/NaY molecular sieve catalyst, and performing column chromatography separation on filtrate to obtain the quinoxaline compound. Compared with the prior art, a method for synthesizing the Yb/NaY molecular sieve catalyst is simple and metal load rate is high; the catalyst is high in thermal stability and easy to store and recycle; device characteristic detection shows that integrated molecular sieve pore passages and crystal structures of the catalyst are maintained; during condensation reaction between the alpha-hydroxyketone and the o-phenylenediamine under the catalysis of Yb/NaY, reaction conditions of are mild, simplicity in operation is ensured, the yield of a target product is 84 to 93 percent, and reduction in the cyclic catalysis efficiency of Yb/NaY is avoided.
- -
-
Paragraph 0058-0061
(2016/11/24)
-
- Synthetic method of quinoxaline heterocyclic compound
-
The invention provides a synthetic method of a quinoxaline heterocyclic compound. A quinoxaline heterocyclic derivative is prepared through one step by carrying out oxidation and cyclic condensation reaction on benzoin and ortho-diamine under the catalysis of a non-transition metal catalyst. According to the method, low-price and easily-available benzoin is used as a raw material, a water-soluble non-transition metal is used as a catalyst and convenient, economical and safe air is used as a direct oxidant to synthesize a target heterocyclic compound through one step at room temperature or a temperature slightly higher than the room temperature; the reaction condition is simple and mild; and inert gas protection is not needed as the synthesis is carried out in the air. The method is easy to operate, the only byproduct is water, the product is simple and easy to separate and purify, the yield is high, and the reaction condition requirement is relatively low, so that the method is wide in application range and has good research and industrial application prospects.
- -
-
Paragraph 0031; 0032
(2016/10/09)
-
- A highly efficient procedure for the synthesis of quinoxaline derivatives using polyvinylpolypyrrolidone supported triflic acid catalyst (PVPP·OTf)
-
A polyvinylpolypyrrolidone supported triflic acid was shown to be useful as a recyclable heterogeneous catalyst for the rapid and efficient synthesis of quinoxaline derivatives in good-to-excellent yields. The catalyst is easily prepared, air-stable, reus
- Khaksar, Samad,Tajbakhsh, Mahmoud,Gholami, Milad,Rostamnezhad, Fariba
-
p. 1287 - 1290
(2014/10/15)
-
- Pentafluorophenylammonium triflate: A highly efficient catalyst for the synthesis of quinoxaline derivatives in water
-
A simple, inexpensive, environmentally friendly and efficient route for the rapid and efficient synthesis of quinoxaline derivatives using pentafluorophenylammonium triflate (PFPAT) as a catalyst is described. Various quinoxaline derivatives were synthesi
- Khaksar, Samad,Radpeyma, Hanieh
-
p. 1023 - 1027
(2014/12/10)
-
- NHC-initiated cascade, metal-free synthesis of quinoxaline derivatives under solvent-free conditions
-
2,3-Diaryl quinoxaline derivatives have been efficiently synthesized by cascade, metal-free, and solvent-free reaction of aryl aldehydes with aryl 1,2-diamines initiated by N-heterocyclic carbene. Compared with reported methods, this procedure has the advantages of easy work-up, reduced energy consumption, and elimination of solvent waste, hazards, and toxicity. A group of potentially bioactive compounds has been prepared for biomedical screening.
- Gao, Lijiu,Liu, Rui,Yu, Chenxia,Yao, Changsheng,Li, Tuanjie,Xiao, Zhaoxin
-
p. 2131 - 2138
(2014/05/06)
-
- Yb modified NaY zeolite: A recyclable and efficient catalyst for quinoxaline synthesis
-
In this study, Yb immobilized NaY zeolite catalyst (Yb/NaY) was obtained by a hydrothermal method and characterized by XRD, BET, FT-IR, ICP-AES, and NH3-TPD. The catalyst displayed good catalytic activity when applied to the synthesis of quinoxalines via condensation of α-hydroxyketones with 1,2-diamines, and could be reused several times without any loss of catalytic activity.
- Fan, Li-Yan,Wei, Lin,Hua, Wen-Jun,Li, Xiang-Xiong
-
supporting information
p. 1203 - 1206
(2014/08/18)
-
- An efficient and one-pot synthesis of benzimidazoles, benzoxazoles, benzothiazoles and quinoxalines catalyzed via nano-solid acid catalysts
-
A simple highly versatile and efficient synthesis of benzimidazoles, benzoxazoles, benzothiazoles, and quinoxalinesis achieved from carbonyl compounds and o-substituted aminoaromatics using nano-sulfated zirconia, nano-structured ZnO, nano-γ-alumina and nano-ZSM-5 zeolites, as the catalyst. The characteristic structural features of the materials were determined by techniques, such as XRD, FT-IR and SEM. The advantages of method are short reaction times and milder conditions and easy work-up. The catalysts can be recovered for the subsequent reactions and reused without any appreciable loss of efficiency.
- Teimouri, Abbas,Chermahini, Alireza Najafi,Salavati, Hossien,Ghorbanian, Leila
-
-
- Assisted tandem catalytic cross metathesis-oxidation: In one flask from styrenes to 1,2-diketones and further to quinoxalines
-
1,2-Diketones were synthesized from styrenes by combining a cross metathesis and a Ru-catalyzed alkene oxidation to an assisted tandem catalytic sequence. The synthesis relies on the use of just one metathesis precatalyst, which was in situ converted to the oxidation catalyst by addition of an alkyl hydroperoxide as a chemical trigger and oxidant. The one-flask sequence can be extended beyond 1,2-diketones to quinoxalines, by condensation of the oxidation products with ortho-phenylenediamine.
- Schmidt, Bernd,Krehl, Stefan,Hauke, Sylvia
-
p. 5427 - 5435
(2013/07/25)
-
- One-pot, facile synthesis of quinoxaline derivatives from bis-aryl α-Hydroxyketones and o-arenediamines using KMnO4/CuSO 4
-
KMnO4/CuSO4, a readily available reagent combination, was found to be effective for the high-yield synthesis of quinoxaline derivatives from bis-aryl α-hydroxyketones and o-arenediamines in hot ethanol.
- Khorramabadi-Zad, Ahmad,Azadmanesh, Mohammad,Mohammadi, Somaye
-
p. 113 - 116
(2013/07/26)
-
- Polystyrene-supported AlCl3 as a highly active and reusable heterogeneous lewis acid catalyst for the one-pot synthesis of quinoxalines
-
A new and environmentally benign protocol for the synthesis of quinoxaline derivatives through the condensation reactions of 1,2-diketones and 1,2-phenylenediamines using cross-linked polystyrene-supported aluminum chloride (PS/AlCl3) as a highly active and reusable heterogeneous Lewis acid catalyst is described. This polymeric catalyst is stable and can be easily recovered and reused without appreciable change in its efficiency. Copyright
- Rahmatpour, Ali
-
p. 472 - 477
(2012/10/29)
-
- A modified synthesis of some novel polycyclic aromatic phenazines and quinoxalines by using the tungstate sulfuric acid (TSA) as a reusable catalyst under solvent-free conditions
-
Considering the synthesis of new compounds, we developed heterocyclic chemistry. We also helped to improve the classical synthetic route for the synthesis of quinoxalines and phenazines through implement in terms of solvent-free reaction. For the condensa
- Karami, Bahador,Khodabakhshi, Saeed,Nikrooz, Marzieh
-
experimental part
p. 187 - 192
(2012/07/16)
-
- Synthesis of novel aryl quinoxaline derivatives by new catalytic methods
-
Quinoxalines are nitrogenous compounds that widely are used in various industries like paint, pharmaceutical and medicine. Quinoxaline ring is also part of antibiotics structure such as Actinomycin, Lomacin. By using of this synthesis method of these comp
- Soleymani, Reza,Niakan, Neda,Tayeb, Shohre,Hakimi, Shirin
-
p. 687 - 701
(2012/10/30)
-
- A Rapid Synthesis of Some 1,4-aryldiazines by the Use of Lithium Chloride as an Effective Catalyst
-
The synthesis of some 1,4-aryldiazines (novel and known dibenzo[a,c]phenazines and quinoxalines) based on the condensation of 1,2-aryldiamines with aromatic 1,2-dicarbonyl compounds in the presence of lithium chloride as a heterogeneous catalyst is presen
- Karami, Bahador,Rooydel, Reza,Khodabakhshi, Saeed
-
experimental part
p. 183 - 188
(2012/06/16)
-
- N-heterocyclic carbene catalyzed one-pot synthesis of 2,3- diarylquinoxalines
-
A one-pot efficient and facile protocol for the direct synthesis of quinoxaline derivatives via tandem N-heterocyclic carbene (NHC)-catalyzed umpolung of aldehydes/oxidation of the benzoins to benzils/condensation of benzils with benzene-1,2-diamines has been developed. Georg Thieme Verlag Stuttgart New York.
- Lin, Yang,Lei, Xiaoli,Yang, Qin,Yuan, Jiangjun,Ding, Qiuping,Xu, Jingshi,Peng, Yiyuan
-
supporting information
p. 2699 - 2706
(2012/11/13)
-
- One-pot synthesis of quinoxalines starting from aldehydes under metal-free conditions
-
An efficient and convenient synthesis of quinoxalines from easily available aldehydes was performed as a one-pot procedure in good to excellent yields under metal-free conditions, via sequential benzoin condensation, aerobic formation of benzils and condensation of the latter with 1,2-diaminobenzenes.
- Hu, Zhong-Yuan,Du, Ding,Tang, Wei-Fang,Lu, Tao
-
p. 2262 - 2264
(2012/08/07)
-
- Efficient, ecofriendly, and practical process for the synthesis of quinoxalines catalyzed by amberlyst-15 in aqueous media
-
Amberlyst-15/H2O has been used as an efficient and environmentally friendly catalytic system for the synthesis of quinoxalines. The present methodology offers several advantages, such as excellent yields, short reaction time, and simple workup. Copyright Taylor & Francis Group, LLC.
- Liu, Ju-Yan,Liu, Jing,Wang, Jia-Di,Jiao, De-Quan,Liu, Hai-Wang
-
experimental part
p. 2047 - 2056
(2010/08/13)
-
- Ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br): A green and neutral reaction media for the efficient, catalyst-free synthesis of quinoxaline derivatives
-
Quinoxaline derivatives were produced in excellent yields and short reaction times via the condensation of 1,2-diamines with 1,2-diketones in the neutral ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br) under catalyst-free and microwave irradia
- Zare, Abdolkarim,Hasaninejad, Alireza,Parhami, Abolfath,Moosavi-Zare, Ahmad Reza,Khedri, Fatemeh,Parsaee, Zahra,Abdolalipoor-Saretoli, Maasoomeh,Khedri, Maasoomeh,Roshankar, Mehrnoosh,Deisi, Hanafieh
-
experimental part
p. 1315 - 1324
(2011/08/06)
-
- Aqueous-phase aerobic oxidation of alcohols by Ru/C in the presence of cyclodextrin: One-pot biomimetic approach to quinoxaline synthesis
-
The aerobic oxidation of alcohols and synthesis of quinoxalines was developed in a one-pot biomimetic approach using recyclable ruthenium on charcoal and randomly methylated β-cyclodextrin in water under neutral conditions overcoming many of the drawbacks in the earlier methodologies. The catalytic system can be recycled up to five cycles without loss of activity. Georg Thieme Verlag Stuttgart New York.
- Akkilagunta, Vijay Kumar,Reddy, Vutukuri Prakash,Kakulapati, Rama Rao
-
supporting information; experimental part
p. 2571 - 2574
(2010/12/20)
-
- Microwave-assisted catalyst-free and solvent-free method for the synthesis of quinoxalines
-
A green and efficient procedure for the synthesis of quinoxalines is reported starting from benzil and 1,2-diaminobenzene. The reactions were carried out under catalyst-free, solvent-free, and microwave-irradiation conditions, affording the corresponding quinoxalines. This method had many dramatic advantages, such as the short reaction time (2-6min), high yields (71-98%), and environmental friendliness, as well as convenient operation.
- Zhou, Jian-Feng,Gong, Gui-Xia,Zhi, San-Jun,Duan, Xiu-Li
-
experimental part
p. 3743 - 3754
(2009/12/06)
-
- Gallium(III) triflate-catalyzed synthesis of quinoxaline derivatives
-
Gallium(III) triflate-catalyzed reactions of phenylene-1,2-diamines and 1,2-diketones produce quinoxalines in excellent to quantitative yields. The reactions proceed with 1 mol % catalyst in ethanol at room temperature. The catalyst can be recycled for at
- Cai, Jing-Jing,Zou, Jian-Ping,Pan, Xiang-Qiang,Zhang, Wei
-
supporting information; scheme or table
p. 7386 - 7390
(2009/05/07)
-
- Metal hydrogen sulfates M(HSO4)n: As efficient catalysts for the synthesis of quinoxalines in EtOH at room temperature
-
A convenient method for the synthesis of quinoxalines catalysed by metal hydrogen sulfates by the reaction of 1,2-diamino compounds and 1,2-dicarbonyl compounds in ethanol as solvent at room temperature is reported.
- Niknam, Khodabakhsh,Zolfigol, Mohammad Ali,Tavakoli, Ziba,Heydari, Zahra
-
experimental part
p. 1373 - 1378
(2009/12/04)
-
- The synthesis of quinoxalines by condensation reaction of acyleins with o-phenylenediamine without solvent under microwave irradiation
-
A convenient synthetic method for 2,3-disubstituted quinoxalines is described. Heating the aryl or alkyl acyloins and o-phenylenediamine in a microwave oven for 3-6 minutes affords 2,3-disubstituted quinoxalines in 20-94% yields.
- Juncai, Feng,Yang, Liu,Qinghua, Meng,Bin, Liu
-
p. 193 - 196
(2007/10/03)
-
- A New Type of Reaction between o-Phenylenediamines and Aromatic Aldehydes to Give 2,3-Diarylquinoxalines
-
A new type of reaction between o-phenylenediamines and aryl aldehydes at high temperature is reported. The synthesis of 2,3-diarylquinoxalines by this procedure is described.
- Ochoa, Carmen,Rodriguez, Juan
-
p. 1053 - 1055
(2007/10/03)
-