23719-78-0

Basic information

• Product Name: 2,3-dibromo-quinoxaline
• Synonyms: 2,3-dibromo-quinoxaline;Quinoxaline, 2,3-dibroMo-
• CAS NO: 23719-78-0
• Molecular Formula: C₈H₄Br₂N₂
• Molecular Weight: 287.94
• Mol File: 23719-78-0.mol

Chemical Properties

• Melting Point: 165-170 °C
• Boiling Point: 313.7±37.0 °C(Predicted)
• Appearance: /
• Density: 2.022±0.06 g/cm3(Predicted)
• PKA: -5.08±0.48(Predicted)
• CAS DataBase Reference: 2,3-dibromo-quinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dibromo-quinoxaline(23719-78-0)
• EPA Substance Registry System: 2,3-dibromo-quinoxaline(23719-78-0)

Safety Data

• Hazardous Substances Data: 23719-78-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2,3-dibromo-quinoxaline is utilized as a building block in the synthesis of pharmaceuticals and agrochemicals due to its unique chemical structure and potential biological activity. Its incorporation into these compounds can enhance their therapeutic or pesticidal properties, making it a valuable component in the development of new drugs and agrochemicals.
Used in Antitumor and Antibacterial Applications:
As a compound with demonstrated antitumor and antibacterial properties, 2,3-dibromo-quinoxaline is used as a therapeutic agent for the treatment of cancer and bacterial infections. Its potential to target and inhibit the growth of tumor cells or bacteria makes it a promising candidate for further research and development in the medical field.
Used in Corrosion Inhibition:
2,3-dibromo-quinoxaline has been studied for its potential use as a corrosion inhibitor, which can protect metals from degradation and extend their lifespan. Its application in this field can contribute to the development of more effective corrosion protection strategies for various industries.
Used in Organic Electronic Materials:
2,3-dibromo-quinoxaline has also been explored for its potential use in organic electronic materials, such as in the development of organic light-emitting diodes (OLEDs) or organic solar cells. Its unique properties may contribute to the enhancement of these materials' performance and efficiency, making it a valuable component in the advancement of organic electronics.

Upstream product

• 34413-35-9 5,6,7,8-tetrahydroquinoxaline 
• 528852-07-5 (R,S)-5-bromo-5,6,7,8-tetrahydroquinoxaline 
• 91-19-0 2,3-diethynylquinoxaline 
• 2423-66-7 quinoxaline 1,4-di-N-oxide 
• 3476-89-9 1,2,3,4-tetrahydroquinoxaline 

Downstream Products

• 676543-54-7 2-amino-3-bromoquinoxaline 
• 676543-67-2 2,2,2-trifluoro-N-(3-phenylethynyl-quinoxalin-2-yl)-acetamide 
• 361390-32-1 2-amino-3-phenylethynylquinoxaline 
• 64802-09-1 2-Phenyl<1H>pyrrolo<2,3-b>quinoxaline 
• 7408-32-4 2,3-bis(3-chlorophenyl)quinoxaline 
• 138476-26-3 2,3-bis(4-chlorophenyl)quinoxaline 
• 6307-64-8 2,3-dimorpholinoquinoxaline 

Relevant articles and documents

Bromination of quinoxaline and derivatives: Effective synthesis of some new brominated quinoxalines

The synthesis of brominated quinoxaline derivatives starting from several kinds of quinoxaline by different bromination strategies was studied. First the synthesis of some brominated quinoxalines was accomplished along with the development of an alternative and effective synthesis of some known compounds. A new, clean, and effective synthetic method for selective reduction of quinoxaline to 1,2,3,4-tetrahydroquinoxaline was also developed. The products obtained were characterized by means of NMR spectroscopy, elemental analyses, and mass spectrometry.

A highly practical and convenient halogenation of fused heterocyclic N-oxides

A novel, simple and practical method for the regioselective halogenation of fused heterocyclic N-oxides has been developed. It employs Vilsmeier reagent, generated in situ by POX3and DMF, as both the activating agent and the nucleophilic halide source. The method is amenable across a broad range of substrates, including quinolines, isoquinolines and the diazine N-oxides, possessing a variety of substitution patterns. Furthermore, all of the reagents associated are cheap and easy to obtain. The potential extension of this method to a one-pot oxidation/halogenation sequence that obviates the need for isolation of the N-oxide intermediates is also presented.